Records 1-30 (of 518 Records) |
Query Trace: HLA-E[original query] |
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Immune response stability to the SARS-CoV-2 mRNA vaccine booster is influenced by differential splicing of HLA genes. Santos-Rebouças Cíntia Barros, et al. Scientific reports 2024 0 0. (1) 8982 |
Evaluation the frequencies of HLA alleles in moderate and severe COVID-19 patients in Iran: A molecular HLA typing study. Abolnezhadian Farhad, et al. Heliyon 2024 0 0. (7) e28528 |
HLA alleles associated with susceptibility and severity of the COVID-19 in Vietnamese. Hai Nguyen Thi Thanh, et al. Human immunology 2024 0 0. 110796 |
Using genetics and proteomics data to identify proteins causally related to COVID-19, healthspan and lifespan: a Mendelian randomization study. Zhao Jie V, et al. Aging 2024 0 0. |
Human leukocyte antigen variants associate with BNT162b2 mRNA vaccine response. Martina Esposito et al. Commun Med (Lond) 2024 4 (1) 63
From the abstract: "We carried out a genome-wide association study to investigate the genetic determinants of the antibody response to the Pfizer-BioNTech vaccine in an Italian cohort of 1351 subjects recruited in three centers. Linear regressions between normalized antibody levels and genotypes of more than 7 million variants was performed, using sex, age, centers, days between vaccination boost and serological test, and five principal components as covariates. We also analyzed the association between normalized antibody levels and 204 HLA alleles, with the same covariates as above. Our study confirms the involvement of the HLA locus and shows significant associations with variants in HLA-A, HLA-DQA1, and HLA-DQB1 genes. In particular, the HLA-A*03:01 allele is the most significantly associated with serum levels of anti-SARS-CoV-2 antibodies. "
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Influence of HLA-A, -B, -DR Polymorphisms on the Severity of COVID-19: A Case-Control Study in the Iranian Population. Mashayekhi Parisa, et al. Archives of Iranian medicine 2024 0 0. (5) 261-266 |
Establishing association between HLA-C*04:01 and severe COVID-19. Warren René L, et al. HLA 2024 0 0. (1) e15355 |
Interaction Between Genetic Susceptibility and COVID-19 Pathogenesis in Pediatric Multisystem Inflammatory Disorders: The Role of Immune Responses. Chen Li-Na, et al. Viral immunology 2024 0 0. |
Genetic and Epigenetic Determinants of COVID-19 Susceptibility: A Systematic Review. Gasmi Amin, et al. Current medicinal chemistry 2024 0 0. |
The role of HLA genetic variants in COVID-19 susceptibility, severity, and mortality: A global review. Hoseinnezhad Taraneh, et al. Journal of clinical laboratory analysis 2024 0 0. |
Genetic determinants of IgG antibody response to COVID-19 vaccination. Bian Shengzhe, et al. American journal of human genetics 2024 0 0. (1) 181-199 |
Lack of association between HLA and asymptomatic SARS-CoV-2 infection. Marchal Astrid, et al. medRxiv : the preprint server for health sciences 2024 0 0. |
Perturbations of the T-cell receptor repertoire in response to SARS-CoV-2 in immunocompetent and immunocompromised individuals. Delmonte Ottavia M, et al. The Journal of allergy and clinical immunology 2023 0 0. |
HLA-B27 did not protect against COVID-19 in patients with axial spondyloarthritis - data from the ReumaCov-Brasil Registry. Mota G D, et al. Advances in rheumatology (London, England) 2023 0 0. (1) 56 |
A web-based genome-wide association study reveals the susceptibility loci of common adverse events following COVID-19 vaccination in the Japanese population. Nogawa Shun, et al. Scientific reports 2023 0 0. (1) 20820 |
HLA-DPB1*013:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID-19. Farias Ticiana D J, et al. HLA 2023 0 0. |
Association of HLA-DRB1*11 and HLA-DRB1*12 gene polymorphism with COVID-19 in Burkina Faso. Ouedraogo Alfred Rakissida, et al. BMC medical genomics 2023 0 0. (1) 246 |
Susceptibility of SARS-CoV2 infection in children. Cotugno Nicola, et al. European journal of pediatrics 2023 0 0. |
HLA alleles: important pieces to the COVID-19 puzzle. Castro-Santos Patricia, et al. Trends in immunology 2023 0 0. |
The HLA advantage: Why COVID-19 benched you but not your co-worker. Saif Nisha, et al. Science immunology 2023 0 0. (87) eadk5067 |
HLA-B*15:01 allele and asymptomatic SARS-CoV-2 infection. Triunfol Marcia, et al. The Lancet. Respiratory medicine 2023 0 0. |
HLA-A*11:01 and HLA-C*04:01 are associated with severe COVID-19. Castro-Santos Patricia, et al. HLA 2023 0 0. |
A Genetic Explanation for Why Some People Had Asymptomatic COVID-19 J Abbasi, JAMA, August 2, 2023
A recent study of COVID-19 infected individuals found that a common variant, or allele, known as HLA-B*15:01 was present in 20% of asymptomatic participants but only 9% of participants who reported symptoms. People with 2 copies of the variant, inherited from both parents, were more than 8 times as likely to not have symptoms than those who carried no copies. The variant also had a strong association with asymptomatic infection in 2 independent cohorts.
A meta-analysis of data from the discovery and independent cohorts found that asymptomatic infections were more than twice as common in people who carried the variant. The T cell analysis revealed that before the pandemic even began, participants with the variant had killer T cells that could effectively target SARS-CoV-2.
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Exploring the Immunomodulatory Properties of Stem Cells in Combating COVID-19: Can We Expect More? Mallis Panagiotis, et al. Bioengineering (Basel, Switzerland) 2023 0 0. (7) |
Genome-wide association studies of response and side effects to the BNT162b2 vaccine in Italian healthcare workers: Increased antibody levels and side effects in carriers of the HLA-A*03:01 allele. Magri Chiara, et al. HLA 2023 0 0. |
HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 era. Buhler Stéphane, et al. HLA 2023 0 0. |
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19. Araújo Adrhyan, et al. Experimental biology and medicine (Maywood, N.J.) 2023 0 0. 15353702231181343 |
A review of the main genetic factors influencing the course of COVID-19 in Sardinia: the role of human leukocyte antigen-G. Mocci Stefano, et al. Frontiers in immunology 2023 0 0. 1138559 |
Multidimensional analysis of immune cells from COVID-19 patients identified cell subsets associated with the severity at hospital admission. Gil-Manso Sergio, et al. PLoS pathogens 2023 0 0. (6) e1011432 |
HLA-DP diversity is associated with improved response to SARS-Cov-2 vaccine in hematopoietic stem cell transplant recipients. Villemonteix Juliette, et al. iScience 2023 0 0. (5) 106763 |
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- Page last updated:Apr 23, 2024
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