Records 1-30 (of 51 Records) |
Query Trace: APOE[original query] |
---|
Family History of Alzheimer's Disease Increases the Risk of COVID-19 Positivity: A SUMS Employees Cohort-based Study. Masoumi Seyed Jalil, et al. Journal of biomedical physics & engineering 2023 0 0. (4) 363-366 |
Apolipoprotein E (ApoE) ε4 Genotype (ApoE rs429358-ApoE rs7412 Polymorphisms) Is Not Associated with Long COVID Symptoms in Previously Hospitalized COVID-19 Survivors. Fernández-de-Las-Peñas César, et al. Genes 2023 0 0. (7) |
ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway. Chen Feng, et al. Journal of translational medicine 2023 0 0. (1) 103 |
APOE4: A Culprit for the Vulnerability of COVID-19 in Alzheimer's Patients. Goyal Ahsas, et al. Current neurovascular research 2023 0 0. |
Apolipoprotein-ε4 allele (APOE-ε4) as a Mediator of Cognitive Loss and Dementia in Long COVID-19. Maiese Kenneth, et al. Current neurovascular research 2023 0 0. |
Targeted screening of genetic associations with COVID-19 susceptibility and severity. Li Ping, et al. Frontiers in genetics 2022 0 0. 1073880 |
Host genetics impact on SARS-CoV-2 vaccine-induced immunoglobulin levels and dynamics: The role of TP53, ABO, APOE, ACE2, HLA-A, and CRP genes. Gemmati Donato, et al. Frontiers in genetics 2022 0 0. 1028081 |
APOE variants affect COVID-19 outcome. Willson Joseph, et al. Nature metabolism 2022 0 0. |
Targeted genetic analysis unveils novel associations between ACE I/D and APO T158C polymorphisms with D-dimer levels in severe COVID-19 patients with pulmonary embolism. Fiorentino Giuseppe, et al. Journal of thrombosis and thrombolysis 2022 0 0. |
Positive Effect of Cognitive Training in Older Adults with Different APOE Genotypes and COVID-19 History: A 1-Year Follow-Up Cohort Study. Zorkina Yana, et al. Diagnostics (Basel, Switzerland) 2022 0 0. (10) |
APOE genotype linked to COVID-19 severity. Le Bras Alexandra, et al. Lab animal 2022 0 0. (11) 282 |
Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity. Gupta Kajal, et al. Gene 2022 0 0. 146790 |
The association of APOE genotype with COVID-19 disease severity. Safdari Lord Javad, et al. Scientific reports 2022 0 0. (1) 13483 |
APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients. Zhang Hongsheng, et al. Signal transduction and targeted therapy 2022 0 0. (1) 261 |
Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis. Dieter Cristine, et al. PloS one 2022 0 0. (7) e0270627 |
Potential protective effect against SARS-CoV-2 infection by APOE rs7412 polymorphism. Espinosa-Salinas Isabel, et al. Scientific reports 2022 0 0. (1) 7247 |
The relationship of early- and late-onset Alzheimer's disease genes with COVID-19. Sirin Seda, et al. Journal of neural transmission (Vienna, Austria : 1996) 2022 0 0. |
A year of Covid-19 GWAS results from the GRASP portal reveals potential genetic risk factors. Thibord Florian, et al. HGG advances 2022 0 0. 100095 |
A year of Covid-19 GWAS results from the GRASP portal reveals potential genetic risk factors F Thibord et al, AJHG, February 22, 2022
In coherence with previous studies, we observed 2 independent signals at the chr3p21.31 locus (rs73062389-A, OR=1.21, P=4.26×10-15 and rs71325088-C, OR=1.62, P=2.25×10-9) modulating susceptibility and severity, respectively, and a signal influencing susceptibility at the ABO locus (rs9411378-A, OR=1.10, P=3.30×10-12), suggesting an increased risk of infection in non-O blood groups carriers. Additional signals at the APOE (associated with severity and death) LRMDA (susceptibility in non-European) and chr2q32.3 (susceptibility in women) loci were also identified but did not replicate in independent datasets.
|
Genomic Characterization of Host Factors Related to SARS-CoV-2 Infection in People with Dementia and Control Populations: The GR@ACE/DEGESCO Study. de Rojas Itziar, et al. Journal of personalized medicine 2021 0 0. (12) |
APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study. Kurki Samu N, et al. Acta neuropathologica communications 2021 0 0. (1) 199 |
The Risk of COVID-19 in People Having a Particular Set of Gene. Dhakal B, et al. Kathmandu University medical journal (KUMJ) 2021 0 0. (74) 265-267 |
A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severity. Zhu Huanhuan, et al. iScience 2021 0 0. 103186 |
Immunoinflammatory role of apolipoprotein E4 in malnutrition and enteric infections and the increased risk for chronic diseases under adverse environments. Freitas Raul S, et al. Nutrition reviews 2021 0 0. |
Hypotheses and facts for genetic factors related to severe COVID-19. Kotsev Stanislav Vasilev, et al. World journal of virology 2021 0 0. (4) 137-155 |
Systematic review of host genetic association with Covid-19 prognosis and susceptibility: What have we learned in 2020? Ferreira de Araújo João Locke, et al. Reviews in medical virology 2021 0 0. e2283 |
Bioinformatic analyses suggest augmented interleukin-17 signaling as the mechanism of COVID-19-associated herpes zoster. Yu Xin, et al. Environmental science and pollution research international 2021 0 0. |
APOE e4 genotypes increase risk of delirium during COVID-19 related hospitalizations: evidence from a large United Kingdom cohort. Kuo Chia-Ling, et al. The journals of gerontology. Series A, Biological sciences and medical sciences 2021 0 0. |
Influence of APOE locus on poor prognosis of COVID-19. Rodrigues Juliana Carla Gomes et al. Heliyon 2021 6 (6) e07379 |
Influence of APOE locus on poor prognosis of COVID-19 JCG Rordrigues et al, Heliyon, June 22, 2021
Data about APOE expression levels was obtained from the Genotype-Tissue Expression Project and the allele frequencies of APOE variants was acquired from the populations included in the phase 3 release of the 1000 Genomes Project. A total of 128 variants showed a significant impact on the APOE expression in lung tissues (p < 0.0001). Linkage Disequilibrium analysis revealed that 98 variants were closely grouped into seven distinct haplotype blocks, of which six were composed of variants that significantly decrease APOE gene expression in the lungs.
|
Disclaimer: Articles listed in the Public Health
Knowledge Base are selected by the CDC Office of Public Health
Genomics to provide current awareness of the literature and news.
Inclusion in the update does not necessarily represent the views of
the Centers for Disease Control and Prevention nor does it imply
endorsement of the article's methods or findings. CDC and DHHS assume
no responsibility for the factual accuracy of the items presented. The
selection, omission, or content of items does not imply any
endorsement or other position taken by CDC or DHHS. Opinion, findings
and conclusions expressed by the original authors of items included in
the update, or persons quoted therein, are strictly their own and are
in no way meant to represent the opinion or views of CDC or DHHS.
References to publications, news sources, and non-CDC Websites are
provided solely for informational purposes and do not imply
endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Apr 23, 2024
- Content source: