Published on 09/24/2020
COVID-19 Genomics and Precision Public Health Weekly Update Content
Pathogen and Human Genomics Studies
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Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics
J Peccia et al, Nature Biotechnology, September 18, 2020We measured SARS-CoV-2 RNA concentrations in primary sewage sludge in the New Haven, Connecticut, during the COVID-19 outbreak in Spring 2020. SARS-CoV-2 RNA was detected throughout the more than 10-week study and, when adjusted for time lags, tracked the rise and fall of cases seen in SARS-CoV-2 clinical test results and local COVID-19 hospital admissions. -
In-Flight Transmission of Severe Acute Respiratory Syndrome Coronavirus 2.
Choi Edward M et al. Emerging infectious diseases 2020 Sep (11)Given the case histories and sequencing results, the most likely sequence of events is that one or both of passengers A and B contracted SARS-CoV-2 in North America and transmitted the virus to flight attendants C and D during the flight. The only location where all 4 persons were in close proximity for an extended period was inside the airplane....Our results strongly suggest in-flight transmission of SARS-CoV-2. -
Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 During Long Flight.
Khanh Nguyen Cong et al. Emerging infectious diseases 2020 Sep (11)We traced 217 passengers and crew to their final destinations and interviewed, tested, and quarantined them. Among the 16 persons in whom SARS-CoV-2 infection was detected, 12 (75%) were passengers seated in business class along with the only symptomatic person (attack rate 62%). Seating proximity was strongly associated with increased infection risk (risk ratio 7.3, 95% CI 1.2?46.2)....In-flight transmission that probably originated from 1 symptomatic passenger caused a large cluster of cases during a long flight. Guidelines for preventing SARS-CoV-2 infection among air passengers should consider individual passengers? risk for infection, the number of passengers traveling, and flight duration. -
Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients.
Lednicky John A et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2020 SepViable (infectious) SARS-CoV-2 was present in aerosols within the hospital room of COVID-19 patients. Airborne virus was detected in the absence of health-care aerosol-generating procedures. The virus strain detected in the aerosols matched the virus strain isolated from a patient with acute COVID-19. -
Studies trace COVID-19 spread to international flights
Van Beusekom M. CIDRAP, Sep 21, 2020.[News story] Three studies published late last week describe in-flight COVID-19 transmission, with one involving a single symptomatic passenger who likely infected at least 12 others during an international flight. [Note: the first two studies are in AMD Clips; the third one, linked here, includes only epi data (no sequencing) so is not in AMD Clips.]
Non-Genomics Precision Health Studies
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Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics
J Peccia et al, Nature Biotechnology, September 18, 2020We measured SARS-CoV-2 RNA concentrations in primary sewage sludge in the New Haven, Connecticut, during the COVID-19 outbreak in Spring 2020. SARS-CoV-2 RNA was detected throughout the more than 10-week study and, when adjusted for time lags, tracked the rise and fall of cases seen in SARS-CoV-2 clinical test results and local COVID-19 hospital admissions. -
In-Flight Transmission of Severe Acute Respiratory Syndrome Coronavirus 2.
Choi Edward M et al. Emerging infectious diseases 2020 Sep (11)Given the case histories and sequencing results, the most likely sequence of events is that one or both of passengers A and B contracted SARS-CoV-2 in North America and transmitted the virus to flight attendants C and D during the flight. The only location where all 4 persons were in close proximity for an extended period was inside the airplane....Our results strongly suggest in-flight transmission of SARS-CoV-2. -
Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 During Long Flight.
Khanh Nguyen Cong et al. Emerging infectious diseases 2020 Sep (11)We traced 217 passengers and crew to their final destinations and interviewed, tested, and quarantined them. Among the 16 persons in whom SARS-CoV-2 infection was detected, 12 (75%) were passengers seated in business class along with the only symptomatic person (attack rate 62%). Seating proximity was strongly associated with increased infection risk (risk ratio 7.3, 95% CI 1.2?46.2)....In-flight transmission that probably originated from 1 symptomatic passenger caused a large cluster of cases during a long flight. Guidelines for preventing SARS-CoV-2 infection among air passengers should consider individual passengers? risk for infection, the number of passengers traveling, and flight duration. -
Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients.
Lednicky John A et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2020 SepViable (infectious) SARS-CoV-2 was present in aerosols within the hospital room of COVID-19 patients. Airborne virus was detected in the absence of health-care aerosol-generating procedures. The virus strain detected in the aerosols matched the virus strain isolated from a patient with acute COVID-19. -
Studies trace COVID-19 spread to international flights
Van Beusekom M. CIDRAP, Sep 21, 2020.[News story] Three studies published late last week describe in-flight COVID-19 transmission, with one involving a single symptomatic passenger who likely infected at least 12 others during an international flight. [Note: the first two studies are in AMD Clips; the third one, linked here, includes only epi data (no sequencing) so is not in AMD Clips.]
News, Reviews and Commentaries
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Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics
J Peccia et al, Nature Biotechnology, September 18, 2020We measured SARS-CoV-2 RNA concentrations in primary sewage sludge in the New Haven, Connecticut, during the COVID-19 outbreak in Spring 2020. SARS-CoV-2 RNA was detected throughout the more than 10-week study and, when adjusted for time lags, tracked the rise and fall of cases seen in SARS-CoV-2 clinical test results and local COVID-19 hospital admissions. -
In-Flight Transmission of Severe Acute Respiratory Syndrome Coronavirus 2.
Choi Edward M et al. Emerging infectious diseases 2020 Sep (11)Given the case histories and sequencing results, the most likely sequence of events is that one or both of passengers A and B contracted SARS-CoV-2 in North America and transmitted the virus to flight attendants C and D during the flight. The only location where all 4 persons were in close proximity for an extended period was inside the airplane....Our results strongly suggest in-flight transmission of SARS-CoV-2. -
Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 During Long Flight.
Khanh Nguyen Cong et al. Emerging infectious diseases 2020 Sep (11)We traced 217 passengers and crew to their final destinations and interviewed, tested, and quarantined them. Among the 16 persons in whom SARS-CoV-2 infection was detected, 12 (75%) were passengers seated in business class along with the only symptomatic person (attack rate 62%). Seating proximity was strongly associated with increased infection risk (risk ratio 7.3, 95% CI 1.2?46.2)....In-flight transmission that probably originated from 1 symptomatic passenger caused a large cluster of cases during a long flight. Guidelines for preventing SARS-CoV-2 infection among air passengers should consider individual passengers? risk for infection, the number of passengers traveling, and flight duration. -
Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients.
Lednicky John A et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2020 SepViable (infectious) SARS-CoV-2 was present in aerosols within the hospital room of COVID-19 patients. Airborne virus was detected in the absence of health-care aerosol-generating procedures. The virus strain detected in the aerosols matched the virus strain isolated from a patient with acute COVID-19. -
Studies trace COVID-19 spread to international flights
Van Beusekom M. CIDRAP, Sep 21, 2020.[News story] Three studies published late last week describe in-flight COVID-19 transmission, with one involving a single symptomatic passenger who likely infected at least 12 others during an international flight. [Note: the first two studies are in AMD Clips; the third one, linked here, includes only epi data (no sequencing) so is not in AMD Clips.]
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- Page last updated:Mar 28, 2024
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