Last data update: Sep 23, 2024. (Total: 47723 publications since 2009)
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Query Trace: Wu JC [original query] |
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Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group
Gurvitz M , Burns KM , Brindis R , Broberg CS , Daniels CJ , Fuller SM , Honein MA , Khairy P , Kuehl KS , Landzberg MJ , Mahle WT , Mann DL , Marelli A , Newburger JW , Pearson GD , Starling RC , Tringali GR , Valente AM , Wu JC , Califf RM . J Am Coll Cardiol 2016 67 (16) 1956-64 Congenital heart disease (CHD) is the most common birth defect, affecting about 0.8% of live births. Advances in recent decades have allowed >85% of children with CHD to survive to adulthood, creating a growing population of adults with CHD. Little information exists regarding survival, demographics, late outcomes, and comorbidities in this emerging group, and multiple barriers impede research in adult CHD. The National Heart, Lung, and Blood Institute and the Adult Congenital Heart Association convened a multidisciplinary working group to identify high-impact research questions in adult CHD. This report summarizes the meeting discussions in the broad areas of CHD-related heart failure, vascular disease, and multisystem complications. High-priority subtopics identified included heart failure in tetralogy of Fallot, mechanical circulatory support/transplantation, sudden cardiac death, vascular outcomes in coarctation of the aorta, late outcomes in single-ventricle disease, cognitive and psychiatric issues, and pregnancy. |
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