Last data update: Sep 16, 2024. (Total: 47680 publications since 2009)
Records 1-2 (of 2 Records) |
Query Trace: Withers PC Jr [original query] |
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The Peculiar epidemiology of dracunculiasis in Chad
Eberhard ML , Ruiz-Tiben E , Hopkins DR , Farrell C , Toe F , Weiss A , Withers PC Jr , Jenks MH , Thiele EA , Cotton JA , Hance Z , Holroyd N , Cama VA , Tahir MA , Mounda T . Am J Trop Med Hyg 2013 90 (1) 61-70 Dracunculiasis was rediscovered in Chad in 2010 after an apparent absence of 10 years. In April 2012 active village-based surveillance was initiated to determine where, when, and how transmission of the disease was occurring, and to implement interventions to interrupt it. The current epidemiologic pattern of the disease in Chad is unlike that seen previously in Chad or other endemic countries, i.e., no clustering of cases by village or association with a common water source, the average number of worms per person was small, and a large number of dogs were found to be infected. Molecular sequencing suggests these infections were all caused by Dracunculus medinensis. It appears that the infection in dogs is serving as the major driving force sustaining transmission in Chad, that an aberrant life cycle involving a paratenic host common to people and dogs is occurring, and that the cases in humans are sporadic and incidental. |
Dracunculiasis eradication: and now, South Sudan
Hopkins DR , Ruiz-Tiben E , Weiss A , Withers PC Jr , Eberhard ML , Roy SL . Am J Trop Med Hyg 2013 89 (1) 5-10 Abstract. This report summarizes the status of the global Dracunculiasis Eradication Program as of the end of 2012. Dracunculiasis (Guinea worm disease) has been eliminated from 17 of 21 countries where it was endemic in 1986, when an estimated 3.5 million cases occurred worldwide. Only 542 cases were reported from four countries in 2012, and 103 villages still had indigenous transmission. Most remaining cases were reported from the new Republic of South Sudan, whereas Chad, Ethiopia, and Mali each reported 10 cases or less. Political instability and insecurity in Mali may become the main obstacles to interrupting dracunculiasis transmission forever. |
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