Last data update: Sep 16, 2024. (Total: 47680 publications since 2009)
Records 1-3 (of 3 Records) |
Query Trace: Sinks TH [original query] |
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Challenges in investigating the association between Agent Orange and cancer: site-specific cancer risk and accuracy of exposure assessment
Sinks TH . Cancer 2014 120 (23) 3595-7 The findings of the study by Yi and Ohrr in the current issue of Cancer add to our overall understanding of the health risks from exposures to Agent Orange. Large numbers of individuals were potentially exposed to Agent Orange during the Vietnam War, and this report reminds us of the critical importance of accurate exposure assessment and the desire for epidemiologic studies to provide scientific clarity, even in the most difficult of circumstances. | The US military in Vietnam removed vegetative cover near base camps, uncovered enemy forces hiding in thick forests, and destroyed food crops available to enemy forces by spraying herbicides, often by aircraft.1 One mixture, Agent Orange, contained 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Individuals involved in mixing, spraying, maintaining, and storing Agent Orange and the other herbicide formulations containing 2,4,5-T were exposed to TCDD. Those who may have been exposed include individuals who contacted herbicide-sprayed vegetation or ingested herbicide-contaminated food or water. This included annually more than 850,000 personnel supporting the Republic of Vietnam, including 36,000 Republic of Korea troops.2 The true number of personnel from either side of the conflict and noncombatant Vietnamese actually exposed to TCDD, and the amount of their exposures, remains unknown. |
Public health assessment of dioxin-contaminated fish at former US airbase, Bien Hoa, Vietnam
Durant JT , Boivin TG , Pohl HR , Sinks TH . Int J Environ Health Res 2014 25 (3) 1-11 Ponds at the former US airbase at Ben Hoa, Vietnam are contaminated with Agent Orange. The ponds had been used for aquaculture, and in all likelihood, fish from those ponds have been sold to the public. We assessed human exposure to 2,3,7,8-tetrachloro-dibenzo-dioxin (2,3,7,8-TCDD) in fish samples from the ponds. For on-base tilapia, muscle concentrations 2,3,7,8-TCDD ranged from 1.4 to 32.7 pg/g. Fat concentrations ranged from 73.3 to 3990 pg/g. Estimated human exposure doses exceed international guidelines and exceed 2,3,7,8-TCDD's lowest adverse effect levels. The Bien Hoa fishponds are a completed human pathway for TCDD exposure. |
Hundreds of partial pipe replacements conducted in Washington D.C. before July 2004: Brown and Sinks respond
Brown MJ , Sinks TH . Environ Res 2011 111 (6) 889 This response to a letter to the Editor by Edwards details the lack of sufficient data for further analyses. |
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