Last data update: Sep 16, 2024. (Total: 47680 publications since 2009)
Records 1-4 (of 4 Records) |
Query Trace: Prakalapakorn SG [original query] |
---|
2021 U.S. Virgin Islands Zika health brigade: Providing recommended pediatric health screenings for children born to mothers with laboratory evidence of possible Zika virus infection during pregnancy
deWilde LH , Harrison CJ , Ceesay BE , Mayers CS , Ferrol-Hawley J , Canton J , Godfred-Cato S , Reynolds MR , Brown-Shuler L , Randhawa S , Schoelles D , Hillman B , Carlos MP , Ambrose T , Bitner D , Holgado S , Jones C , Lattin DJ , Mulkey SB , Nguyen A , Payne M , Prakalapakorn SG , Shue A , Ellis EM . Birth Defects Res 2022 BACKGROUND: The United States Virgin Islands (USVI) Department of Health (DOH) conducted a second Zika health brigade (ZHB) in 2021 to provide recommended Zika-related pediatric health screenings, including vision, hearing, neurologic, and developmental screenings, for children in the USVI. This was replicated after the success of the first ZHB in 2018, which provided recommended Zika-related pediatric health screenings to 88 infants and children exposed to Zika virus (ZIKV) during pregnancy. METHODS: Ten specialty pediatric care providers were recruited and traveled to the USVI to conduct the screenings. USVI DOH scheduled appointments for children included in CDC's U.S. Zika Pregnancy and Infant Registry (USZPIR). During the ZHB, participants were examined by pediatric ophthalmologists, pediatric audiologists, and pediatric neurologists. We report the percentage of participants who were referred for additional follow-up care or given follow-up recommendations in the 2021 ZHB and compare these referrals and recommendations to those given in the 2018 ZHB. RESULTS: Thirty-three children born to mothers with laboratory evidence of ZIKV infection during pregnancy completed screenings at the 2021 ZHB, of which 15 (45%) children were referred for additional follow-up care. Ophthalmological screenings resulted in the highest number of new referrals for a specialty provider among ZHB participants, with 6 (18%) children receiving referrals for that specialty. Speech therapy was the most common therapy referral, with 10 (30%) children referred, of which 9 (90%) were among those who attended the 2018 ZHB. CONCLUSIONS: Thirty-three children in a jurisdiction with reduced access to healthcare specialists received recommended Zika-related pediatric health screenings at the ZHB. New and continuing medical and developmental concerns were identified and appropriate referrals for follow-up care and services were provided. The ZHB model was successful in creating connections to health services not previously received by the participants. |
Ocular Findings and Visual Function in Children Examined during the Zika Health Brigade in the US Virgin Islands, March 2018
Prakalapakorn SG , Bonafede L , Lawrence L , Lattin D , Kim N , House RD , Hillman B , de Wilde L , Harrison C , Fehrenbach N , Godfred-Cato S , Reynolds MR , Ellis EM . Trop Med Infect Dis 2021 6 (2) Among children born with laboratory-confirmed Zika virus (ZIKV) infection, visual impairment (VI) can occur despite normal ocular structure. The objective of this report is to describe ocular findings and visual function among children examined during the Department of Health Zika Health Brigade (ZHB) in the United States Virgin Islands in March 2018. This analysis is based on a retrospective chart review of children eligible to participate in the ZHB (i.e., part of the US Zika Pregnancy and Infant Registry) and who were examined by ophthalmologists. Eighty-eight children attended the ZHB. This report includes 81 children [48 (59.3%) males] whose charts were located [average gestational age = 37.6 weeks (range: 27.6-41.3) and average adjusted age at examination = 9.1 months (range: 0.9-21.9)]. Of those examined, 5/81 (6.2%) had microcephaly at birth, 2/81 (2.5%) had a structural eye abnormality, and 19/72 (26.4%) had VI. Among children with normal ocular structure and neurologic examination, 13/51 (25.5%) had VI. Despite a low incidence of abnormal ocular structure and microcephaly, about a quarter of children examined had VI. Our findings emphasize that ophthalmological examinations should be performed in all children with suspicion for antenatal ZIKV infection, even children with normal ocular structure and neurologic examination. |
The eyes as a window to improved understanding of the prenatal effects of Zika virus infection
Prakalapakorn SG , Meaney-Delman D , Honein MA , Rasmussen SA . J AAPOS 2017 21 (4) 259-261 Much has been learned about Zika virus (ZIKV) | since the World Health Organization first reported | mosquito-borne transmission of ZIKV | in the Americas in Brazil in May of 2015.1 Historically, | ZIKV has been known to be transmitted by an arthropod | vector, but recently additional modes of transmission | have been identified, including sexual, intrauterine, and | perinatal.2 And although most people with ZIKV infection | are asymptomatic or only mildly affected, ZIKV has | recently been recognized to be associated with Guillain- | Barre syndrome, with about 1 in 4,000 persons infected | with ZIKV later developing the neurologic disorder.2 Of | most critical significance, a causal relationship between | prenatal ZIKV infection and serious brain anomalies and | microcephaly has recently been identified.3 A distinctive | constellation of anomalies has emerged and has been | defined as congenital Zika syndrome (CZS).4 |
Assessment of risk factors for infantile cataracts using a case-control study National Birth Defects Prevention Study, 2000-2004
Prakalapakorn SG , Rasmussen SA , Lambert SR , Honein MA . Ophthalmology 2010 117 (8) 1500-5 OBJECTIVE: To identify risk factors for infantile cataracts of unknown etiology. DESIGN: Case-control study. PARTICIPANTS: Case infants (n = 152) and control infants (n = 4205) enrolled in the National Birth Defects Prevention Study for birth years 2000-2004. METHODS: Multivariate analysis was performed exploring associations for risk factors for bilateral and unilateral infantile cataracts of unknown etiology. MAIN OUTCOME MEASURES: Infantile cataracts of unknown etiology. RESULTS: Maternal interviews were completed for 43 case infants with bilateral and 109 with unilateral infantile cataracts of unknown etiology. Very low birth weight (<1500 g) was associated with both unilateral (adjusted odds ratio [OR], 6.0; 95% confidence interval [CI], 2.2-16.3) and bilateral (OR, 13.2; 95% CI, 4.2-41.1) cataracts, whereas low birth weight (1500-2499 g) was only associated with bilateral cataracts (OR, 3.3; 95% CI, 1.3-8.1). Infants with unilateral cataracts were more likely to be born to primigravid women (OR, 1.6; 95% CI, 1.0-2.7) than women with ≥2 previous pregnancies, although this was of borderline significance. Although not significant, effect estimates were elevated suggesting a possible association between unilateral cataracts and maternal substance abuse during pregnancy, and between bilateral cataracts and urinary tract infection during pregnancy and aspirin use during pregnancy. CONCLUSIONS: Very low birth weight is associated with both bilateral and unilateral cataracts, whereas low birth weight is associated with bilateral cataracts and primigravidity with unilateral cataracts. Other associations, although not statistically significant, suggest risk factors that merit further research. FINANCIAL DISCLOSURES: The authors have no proprietary or commercial interest in any of the materials discussed in this article. |
- Page last reviewed:Feb 1, 2024
- Page last updated:Sep 16, 2024
- Content source:
- Powered by CDC PHGKB Infrastructure