Last data update: Jun 03, 2024. (Total: 46935 publications since 2009)
Records 1-7 (of 7 Records) |
Query Trace: Piacitelli L [original query] |
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Exposures and cross-shift lung function declines in wildland firefighters
Gaughan DM , Piacitelli CA , Chen BT , Law BF , Virji MA , Edwards NT , Enright PL , Schwegler-Berry DE , Leonard SS , Wagner GR , Kobzik L , Kales SN , Hughes MD , Christiani DC , Siegel PD , Cox-Ganser JM , Hoover MD . J Occup Environ Hyg 2014 11 (9) 591-603 Respiratory problems are common among wildland firefighters. However, there are few studies directly linking occupational exposures to respiratory effects in this population. Our objective was to characterize wildland fire fighting occupational exposures and assess their associations with cross-shift changes in lung function. We studied 17 members of the Alpine Interagency Hotshot Crew with environmental sampling and pulmonary function testing during a large wildfire. We characterized particles by examining size distribution and mass concentration, and conducting elemental and morphological analyses. We examined associations between cross-shift lung function change and various analytes, including levoglucosan, an indicator of wood smoke from burning biomass. The levoglucosan component of the wildfire aerosol showed a predominantly bimodal size distribution: a coarse particle mode with a mass median aerodynamic diameter about 12 mum and a fine particle mode with a mass median aerodynamic diameter < 0.5 mum. Levoglucosan was found mainly in the respirable fraction and its concentration was higher for fire line construction operations than for mop-up operations. Larger cross-shift declines in forced expiratory volume in one second were associated with exposure to higher concentrations of respirable levoglucosan (p < 0.05). Paired analyses of real-time personal air sampling measurements indicated that higher carbon monoxide (CO) concentrations were correlated with higher particulate concentrations when examined by mean values, but not by individual data points. However, low CO concentrations did not provide reliable assurance of concomitantly low particulate concentrations. We conclude that inhalation of fine smoke particles is associated with acute lung function decline in some wildland firefighters. Based on short-term findings, it appears important to address possible long-term respiratory health issues for wildland firefighters. [Supplementary materials are available for this article. Go to the publisher's online edition of Journal of Occupational and Environmental Hygiene for the following free supplemental resources: a file containing additional information on historical studies of wildland fire exposures, a file containing the daily-exposure-severity questionnaire completed by wildland firefighter participants at the end of each day, and a file containing additional details of the investigation of correlations between carbon monoxide concentrations and other measured exposure factors in the current study.]. |
Respiratory symptoms and lung function abnormalities related to work at a flavouring manufacturing facility
Cummings KJ , Boylstein RJ , Stanton ML , Piacitelli CA , Edwards NT , LeBouf RF , Kreiss K . Occup Environ Med 2014 71 (8) 549-54 OBJECTIVES: To better understand respiratory symptoms and lung function in flavouring manufacturing workers. METHODS: We offered a questionnaire and lung function testing to the current workforce of a flavouring manufacturing facility that had transitioned away from diacetyl and towards substitutes in recent years. We examined symptoms, spirometric parameters and diffusing capacity measurements by exposure variables, including facility tenure and time spent daily in production areas. We used linear and logistic regression to develop final models adjusted for age and smoking status. RESULTS: A total of 367 (93%) current workers participated. Shortness of breath was twice as common in those with tenure ≥7 years (OR 2.0, 95% CI 1.1 to 3.6). Other chest symptoms were associated with time spent daily in production. Participants who spent ≥1 h daily in production areas had twice the odds of any spirometric abnormality (OR 2.3; 95% CI 1.1 to 5.3) and three times the odds of low diffusing capacity (OR 2.8; 95% CI 0.9 to 9.4) than other participants. Mean spirometric parameters were significantly lower in those with tenure ≥7 years and those who spent ≥1 h daily in production. Mean diffusing capacity parameters were significantly lower in those with tenure ≥7 years. Differences in symptoms and lung function could not be explained by age, smoking status or employment at another flavouring plant. CONCLUSIONS: Symptoms and lung function findings were consistent with undiagnosed or subclinical obliterative bronchiolitis and associated with workplace exposures. Further efforts to lower exposures to flavouring chemicals, including diacetyl substitutes, are warranted. |
Vocal cord dysfunction related to water-damaged buildings
Cummings KJ , Fink JN , Vasudev M , Piacitelli C , Kreiss K . J Allergy Clin Immunol Pract 2013 1 (1) 46-50 Vocal cord dysfunction (VCD) is the intermittent paradoxical adduction of the vocal cords during respiration, resulting in variable upper airway obstruction. Exposure to damp indoor environments is associated with adverse respiratory health outcomes, including asthma, but its role in the development of VCD is not well described. We describe the spectrum of respiratory illness in occupants of 2 water-damaged office buildings. The National Institute for Occupational Safety and Health conducted a health hazard evaluation that included interviews with managers, a maintenance officer, a remediation specialist who had evaluated the 2 buildings, employees, and consulting physicians. In addition, medical records and reports of building evaluations were reviewed. Diagnostic evaluations for VCD had been conducted at the Asthma and Allergy Center of the Medical College of Wisconsin. Two cases of VCD were temporally related to occupancy of water-damaged buildings. The patients experienced cough, chest tightness, dyspnea, wheezing, and hoarseness when in the buildings. Spirometry was normal. Methacholine challenge did not show bronchial hyperreactivity but did elicit symptoms of VCD and inspiratory flow-volume loop truncation. Direct laryngoscopy revealed vocal cord adduction during inspiration. Coworkers developed upper and lower respiratory symptoms; their diagnoses included sinusitis and asthma, consistent with recognized effects of exposure to indoor dampness. Building evaluations provided evidence of water damage and mold growth. VCD can occur with exposure to water-damaged buildings and should be considered in exposed patients with asthma-like symptoms. |
Efficacy of the revised NIOSH lifting equation to predict risk of low back pain due to manual lifting: expanded cross-sectional analysis
Waters TR , Lu ML , Piacitelli LA , Werren D , Deddens JA . J Occup Environ Med 2011 53 (9) 1061-7 OBJECTIVE: To evaluate whether the Revised NIOSH Lifting Equation (RNLE) is a valid tool for assessing risk of low back pain (LBP) due to manual lifting by using combined data from two cross-sectional studies of 1-year prevalence. METHODS: Results from a symptom and occupational history questionnaire and RNLE analysis for 677 subjects employed in 125 manual lifting jobs at nine industrial sites were combined from two studies. RESULTS: The odds of LBP increased as the lifting index (LI) increased from 1.0 to 3.0. A statistically significant odds ratio (OR) was found for both the 1 < LI ≤ 2 (OR = 1.81) and the 2 < LI ≤ 3 categories (OR = 2.26). For jobs with an LI value greater than 3.0, however, the OR remained nonsignificant. The 2 < LI ≤ 3 group remained statistically significant after adjusting for age, gender, body mass index, and psychosocial factors. CONCLUSIONS: It is clear that as the LI increases, the risk of LBP increases. Longitudinal studies are needed. |
Human posture simulation to assess cumulative spinal load due to manual lifting. Part I: methods
Waters TR , Lu M , Werren D , Piacitelli L . Theor Issues Ergon Sci 2011 12 (2) 176-188 The estimation of cumulative spinal load (CSL) resulting from exposure to manual materials handling (MMH) may provide a sensitive method for assessing the risk of highly varying exposures. This article reports on a CSL method that involves human posture simulation of workers from videotape in order to assess spinal load exposures due to MMH. The proposed method appears to be sensitive to different durations of exposure, easy to use and useful for assessing jobs with a high degree of variability in task characteristics between lifts. Although the method remains to be validated, it appears to be a useful addition to the range of tools available for assessing manual lifting exposures in worksite-based epidemiologic studies. Ergonomic methods are lacking for assessing highly variable MMH tasks, such as tasks found in warehousing. The existing methods do not include sufficient factors to account for variable exposure patterns or tasks with highly variable task characteristics, such as varying load weights and lift geometries. The CSL assessment method described in this article may provide a way to evaluate these types of tasks in order to assess the overall risk of workers developing work-related musculoskeletal disorders. |
Human posture simulation to assess cumulative spinal load due to manual lifting. Part II: accuracy and precision
Lu M , Waters T , Werren D , Piacitelli L . Theor Issues Ergon Sci 2011 12 (2) 189-203 For assessing a large number of variable manual lifting jobs, posture specification for using the University of Michigan Three Dimensional Static Strength Prediction Program and the revised National Institute for Occupational Safety and Health Lifting Equation may be time-consuming, tedious and subject to human errors. To expedite data analysis with desirable accuracy and precision for the two risk assessment tools, a new data analysis method based on human posture simulation was developed and evaluated. The accuracy and precision of the posture simulation method were evaluated by a repeated measures study design with six postures, three viewing angles and three trial repetitions as experimental factors. The effects of the experimental factors on the average accuracy and precision of the simulation method are reported and discussed. The study results also demonstrated pros and cons of human posture simulation as a means of posture specification for ergonomic risk assessments. The findings about the accuracy and precision of the human posture simulation method for quantifying the risk of musculoskeletal disorders due to manual materials handling may provide researchers with a new way of ergonomic assessments. |
Correcting diacetyl concentrations from air samples collected with NIOSH Method 2557
Cox-Ganser J , Ganser G , Saito R , Hobbs G , Boylstein R , Hendricks W , Simmons M , Eide M , Kullman G , Piacitelli C . J Occup Environ Hyg 2011 8 (2) 59-70 Diacetyl (2,3-butanedione), a diketone chemical used to impart a buttery taste in many flavoring mixtures, has been associated with bronchiolitis obliterans in several industrial settings. For workplace evaluations in 2000-2006, National Institute for Occupational Safety and Health (NIOSH) investigators used NIOSH Method 2557, a sampling and analytical method for airborne diacetyl utilizing carbon molecular sieve sorbent tubes. The method was subsequently suspected to progressively underestimate diacetyl concentrations with increasing sampling site humidity. Since underestimation of worker exposure may lead to overestimation of respiratory health risk in quantitative exposure-effect analyses, correction of the diacetyl concentrations previously reported with Method 2557 is essential. We studied the effects of humidity and sample storage duration on recovery of diacetyl from experimental air samples taken from a dynamically generated controlled test atmosphere that allowed control of diacetyl concentration, temperature, relative humidity, sampling duration, and sampling flow rate. Samples were analyzed with Method 2557, and results were compared with theoretical test atmosphere diacetyl concentration. After fitting nonlinear models to the experimental data, we found that absolute humidity, diacetyl concentration, and days of sample storage prior to extraction affected diacetyl recovery as did sampling flow rate to a much smaller extent. We derived a mathematical correction procedure to more accurately estimate historical workplace diacetyl concentration based on laboratory-reported concentrations of diacetyl using Method 2557, and sample site temperature and relative humidity (to calculate absolute humidity), as well as days of sample storage prior to extraction in the laboratory. With this correction procedure, quantitative risk assessment for diacetyl can proceed using corrected exposure levels for air samples previously collected and analyzed using NIOSH Method 2557 for airborne diacetyl. |
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