Last data update: Sep 16, 2024. (Total: 47680 publications since 2009)
Records 1-2 (of 2 Records) |
Query Trace: Moore MS [original query] |
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Notes from the field: Fungal bloodstream infections associated with a compounded intravenous medication at an outpatient oncology clinic - New York City, 2016
Vasquez AM , Lake J , Ngai S , Halbrook M , Vallabhaneni S , Keckler MS , Moulton-Meissner H , Lockhart SR , Lee CT , Perkins K , Perz JF , Antwi M , Moore MS , Greenko J , Adams E , Haas J , Elkind S , Berman M , Zavasky D , Chiller T , Ackelsberg J . MMWR Morb Mortal Wkly Rep 2016 65 (45) 1274-1275 On May 24, 2016, the New York City Department of Health and Mental Hygiene notified CDC of two cases of Exophiala dermatitidis bloodstream infections among patients with malignancies who had received care from a single physician at an outpatient oncology facility (clinic A). Review of January 1-May 31, 2016 microbiology records identified E. dermatitidis bloodstream infections in two additional patients who also had received care at clinic A. All four patients had implanted vascular access ports and had received intravenous (IV) medications, including a compounded IV flush solution containing saline, heparin, vancomycin, and ceftazidime, compounded and administered at clinic A. |
Hepatocellular carcinoma and viral hepatitis in New York City
Moore MS , Ivanina E , Bornschlegel K , Qiao B , Schymura MJ , Laraque F . Clin Infect Dis 2016 63 (12) 1577-1583 BACKGROUND: Hepatocellular carcinoma (HCC) incidence and mortality are increasing in the United States. Viral hepatitis infection is a primary risk factor for HCC. This study describes the relationship between viral hepatitis and HCC in New York City (NYC). METHODS: Viral hepatitis cases reported to the NYC Department of Health from 1999-2012 were matched to HCC cases diagnosed from 2001-2012 and reported to the New York State Cancer Registry. HCC cases were stratified by presence or absence of viral hepatitis. Demographic characteristics, factors associated with specific causes of death, and survival time were analyzed for all HCC cases. RESULTS: From 2001-2012, 8,827 NYC residents were diagnosed with HCC; 38.4% had hepatitis C (HCV) infection, 17.9% had hepatitis B (HBV) infection, and 2.2% had both infections. HCC patients were predominantly men (74.8%) and equally white non-Hispanic (28.6%) and Hispanic (28.9%). Those with HBV were primarily Asian/Pacific Islander (63.2%). The median survival time after HCC diagnosis for persons with HBV infection was 22.3 months, compared with 13.1 months for persons with HCV, and 6.9 months for non-infected persons. The five-year survival rate was 37.5% for those with HBV, 20.0% for those with HCV, 29.5% among coinfected individuals, and 16.1% for those with neither infection reported. CONCLUSION: In NYC, most persons with HCC have viral hepatitis; the majority of viral hepatitis infections are due to HCV. Survival for persons with HCC differs widely by viral hepatitis status. This study highlights the importance of viral hepatitis prevention and treatment and HCC screening. |
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