Last data update: Sep 16, 2024. (Total: 47680 publications since 2009)
Records 1-7 (of 7 Records) |
Query Trace: McQueen S [original query] |
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Commentary on a meeting entitled 'Building global capacity for non-communicable diseases (NCD) prevention: Defining direction and roles'
McQueen D , Pratt M , Blanchard C . Glob Health Promot 2013 20 93-6 This Commentary summarizes the key points that arose during a three-day meeting held in Atlanta in July 2012 on Building Global Capacity for NCD Prevention. A wide spectrum of participants representing many sectors of global health, including ministries of health from several low and middle-income countries (LMICs), governmental institutions, non-governmental organizations, national disease associations, academia, and global and regional institutions participated. Presentations and group discussions led to agreement on a number of actions that should be taken to increase capacity for coping with NCDs in LMICs. Key areas of discussion were on the role of research, workforce development, resources, and governance. While there was considerable agreement on what should be done, the workshop participants had difficulty in prioritizing these activities. This led to an agreement by the gathered participants that a follow-up Delphi study be conducted to help with prioritization. |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
Lill CM , Roehr JT , McQueen MB , Kavvoura FK , Bagade S , Schjeide BM , Schjeide LM , Meissner E , Zauft U , Allen NC , Liu T , Schilling M , Anderson KJ , Beecham G , Berg D , Biernacka JM , Brice A , DeStefano AL , Do CB , Eriksson N , Factor SA , Farrer MJ , Foroud T , Gasser T , Hamza T , Hardy JA , Heutink P , Hill-Burns EM , Klein C , Latourelle JC , Maraganore DM , Martin ER , Martinez M , Myers RH , Nalls MA , Pankratz N , Payami H , Satake W , Scott WK , Sharma M , Singleton AB , Stefansson K , Toda T , Tung JY , Vance J , Wood NW , Zabetian CP , Young P , Tanzi RE , Khoury MJ , Zipp F , Lehrach H , Ioannidis JP , Bertram L . PLoS Genet 2012 8 (3) e1002548 More than 800 published genetic association studies have implicated dozens of potential risk loci in Parkinson's disease (PD). To facilitate the interpretation of these findings, we have created a dedicated online resource, PDGene, that comprehensively collects and meta-analyzes all published studies in the field. A systematic literature screen of ~27,000 articles yielded 828 eligible articles from which relevant data were extracted. In addition, individual-level data from three publicly available genome-wide association studies (GWAS) were obtained and subjected to genotype imputation and analysis. Overall, we performed meta-analyses on more than seven million polymorphisms originating either from GWAS datasets and/or from smaller scale PD association studies. Meta-analyses on 147 SNPs were supplemented by unpublished GWAS data from up to 16,452 PD cases and 48,810 controls. Eleven loci showed genome-wide significant (P < 5 x 10(-8)) association with disease risk: BST1, CCDC62/HIP1R, DGKQ/GAK, GBA, LRRK2, MAPT, MCCC1/LAMP3, PARK16, SNCA, STK39, and SYT11/RAB25. In addition, we identified novel evidence for genome-wide significant association with a polymorphism in ITGA8 (rs7077361, OR 0.88, P = 1.3 x 10(-8)). All meta-analysis results are freely available on a dedicated online database (www.pdgene.org), which is cross-linked with a customized track on the UCSC Genome Browser. Our study provides an exhaustive and up-to-date summary of the status of PD genetics research that can be readily scaled to include the results of future large-scale genetics projects, including next-generation sequencing studies. |
Is the accuracy of self-reported colorectal cancer screening associated with social desirability?
Vernon SW , Abotchie PN , McQueen A , White A , Eberth JM , Coan SP . Cancer Epidemiol Biomarkers Prev 2012 21 (1) 61-5 BACKGROUND: Self-reported cancer screening behaviors are often overreported and may lead to biased estimates of prevalence and of subgroup differences in screening. We examined whether the tendency to give socially desirable responses was associated with concordance between self-reported colorectal cancer (CRC) screening behaviors and medical records. METHODS: Primary care patients (n = 857) age 50 to 74 years completed a mail, face-to-face, or telephone survey that assessed CRC screening and social desirability measured by a short version of the Marlowe-Crowne scale. We used medical records to verify self-reports of fecal occult blood testing (FOBT), sigmoidoscopy, colonoscopy, and barium enema. RESULTS: Social desirability scores were lower for whites versus African Americans, college graduates, and patients reporting no prior screening tests; they were higher for telephone versus mail or face-to-face survey respondents. In univariable logistic regression analysis, social desirability scores were not associated with concordance for FOBT (OR = 1.03, 95% CI = 0.94-1.13), sigmoidoscopy (OR = 0.95, 95% CI = 0.86-1.04), or colonoscopy (OR = 0.99, 95% CI = 0.88-1.11); however, lower social desirability scores were associated with increased concordance for barium enema (OR = 0.87, 95% CI = 0.77-0.99). In multivariable analyses, no associations were statistically significant. CONCLUSION: Social desirability as measured by the Marlowe-Crowne scale was not associated with accuracy of self-reported CRC tests in our sample, suggesting that other explanations for overreporting need to be explored. IMPACT: By understanding sources of response bias, we can improve the accuracy of self-report measures. (Cancer Epidemiol Biomarkers Prev; 21(1); 61-65. (c)2011 AACR.) |
The Tanzania Field Epidemiology and Laboratory Training Program: building and transforming the public health workforce
Mmbuji P , Mukanga D , Mghamba J , Ahly M , Mosha F , Azima S , Senga S , Moshiro C , Semali I , Rolle I , Wiktor S , McQueen S , McElroy P , Nsubuga P . Pan Afr Med J 2011 10 9 The Tanzania Field Epidemiology and Laboratory Training Program (TFELTP) was established in 2008 as a partnership among the Ministry of | Health and Social Welfare (MOHSW), Muhimbili University of Health and Allied Sciences, National Institute for Medical Research, and local and | international partners. TFELTP was established to strengthen the capacity of MOHSW to conduct public health surveillance and response, manage national disease control and prevention programs, and to enhance public health laboratory support for surveillance, diagnosis, treatment and disease monitoring. TFELTP is a 2-year full-time training program with approximately 25% time spent in class, and 75% in the field. TFELTP offers two tracks leading to an MSc degree in either Applied Epidemiology or, Epidemiology and Laboratory Management. Since 2008, the program has enrolled a total of 33 trainees (23 males, 10 females). Of these, 11 were enrolled in 2008 and 100% graduated in 2010. All 11 graduates of cohort 1 are currently employed in public health positions within the country. Demand for the program as measured by the number of applicants has grown from 28 in 2008 to 56 in 2011. While training the public health leaders of the country, TFELTP has also provided essential service to the country in responding to high-profile disease outbreaks, and evaluating and improving its public health surveillance systems and diseases control programs. TFELTP was involved in the country assessment of the revised International Health Regulations (IHR) core capabilities, development of the Tanzania IHR plan, and incorporation of IHR into the revised Tanzania Integrated Disease Surveillance and Response (IDSR) guidelines. TFELTP is training a competent core group of public health leaders for Tanzania, as well as providing much needed service to the MOHSW in the areas of routine surveillance, outbreak detection and response, and disease program management. However, the immediate challenges that the program must address include development of a full range of in-country teaching capacity for the program, as well as a career path for graduates. |
Correspondence to Sand et Al. "Critical reappraisal of a catechol-o-methyltransferase transversion variant in schizophrenia".
Lill CM , Schjeide BM , Roehr JT , Zauft U , Allen NC , Zipp F , McQueen MB , Kavvoura FK , Ioannidis JP , Khoury MJ , Tanzi RE , Bertram L . Biol Psychiatry 2010 67 (7) e45-8 Recently, Sand et al. (1) published a Correspondence to the Editor of Biological Psychiatry (1), in which they have “reappraised” published evidence on the potential association between schizophrenia risk and a genetic variant (rs4818) in the COMT gene. Although posted as correspondence to the pharmacogenetic study by Roussos et al. (2), the letter by Sand et al. in fact represents this group's latest addition to a string of similar correspondences “deconstructing” the work of other research groups (3, 4, 5, 6, 7, 8). This time, they take aim at the SchizophreniaGene (SZGene) website (http://www.szgene.org)—a freely available database launched in 2007 that systematically collects and meta-analyzes published genetic association studies in schizophrenia—created and maintained by our group (9). After listing a number of alleged errors and “misconceptions” by the SzGene curators, Sand et al. conclude that “in its 6th year [sic] of operation, SZGene continues to be burdened with shortcomings that call into question its utility as a meta-analytic tool of reference.” Below, we address the most significant accusations of Sand et al., illuminate their relevance to the potential association between COMT and schizophrenia, and discuss their bearing on the SZGene approach as a whole. |
25 years of HBSC: challenges and successes
McQueen DV . Int J Public Health 2009 54 123-4 In today’s world there are many surveys and many of those | are surveys of children, but none possess the three salient | characteristics that have defined the HBSC: 1. it has been | sustained over a long period of time, more than a quarter | century; 2. it has built survey research capacity over that time | in many and varied countries; and 3. it is driven by an underlying theoretical approach that is informative, innovative | and sensitive to the leading issues of the time. Each of these | characteristics is a considerable challenge to any collective | knowledge seeking endeavor. Sustainability is difficult in any | scientific undertaking. Funding sources often suffer from the | political whims of decision makers in governments that vary | over time. Maintaining funding may not be as problematic | for large scale projects in the physical or biological sciences | because they are less likely to be seen as bound to societal | prejudices. However, a subject area such as health related | behaviour in school children is potentially much more sensitive to trends and views of current policies, because of the | age of respondents as well as content, such as sexual activity | and risk behaviours. Even where friendly policies do last over | many years, resources may vary in the same time period. Thus | for a funding body to consistently rate this survey as worthy of | continued support, the result is highly valued. Although each | participating country can tell its own story of sustainability, | some with more success than others, the point is that the whole | endeavor has been sustained and that is to be admired |
Domains of core competency, standards, and quality assurance for building global capacity in health promotion: the Galway consensus conference statement
Allegrante JP , Barry MM , Airhihenbuwa CO , Auld ME , Collins JL , Lamarre MC , Magnusson G , McQueen DV , Mittelmark MB , Galway Consensus Conference . Health Educ Behav 2009 36 (3) 476-82 This paper reports the outcome of the Galway Consensus Conference, an effort undertaken as a first step toward international collaboration on credentialing in health promotion and health education. Twenty-nine leading authorities in health promotion, health education, and public health convened a 2-day meeting in Galway, Ireland, during which the available evidence on credentialing in health promotion was reviewed and discussed. Conference participants reached agreement on core values and principles, a common definition, and eight domains of core competency required to engage in effective health promotion practice. The domains of competency are catalyzing change, leadership, assessment, planning, implementation, evaluation, advocacy, and partnerships. The long-term aim of this work is to stimulate a global dialogue that will lead to the development and widespread adoption of standards and quality assurance systems in all countries to strengthen capacity in health promotion, a critical element in achieving goals for the improvement of global population health. |
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