Cigarette smoking is the leading cause of preventable disease, disability, and death in the U.S.1 Each year, nearly half a million U.S. adults die prematurely of smoking or exposure to secondhand smoke. In addition, >16 million live with a serious illness caused by smoking. In addition to these human costs, smoking-related disease among adults costs the U.S. >$300 billion each year, including $170 billion in direct medical care and >$150 billion in lost productivity owing to premature death. | | Since the 1960s, current cigarette smoking prevalence has decreased markedly among U.S. adults, declining by 70% among men and 64% among women as of 2017.2 Despite this progress, 14% of U.S. adults (34.1 million people) were still current smokers in 2019.3 Furthermore, smoking prevalence remains high among certain population subgroups, including people who are less educated; people living below the poverty line; people who are lesbian, gay, or bisexual; people living with behavioral health concerns; and people of certain races and ethnicities.2