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COVID-10 GPH

Last data update: Apr 28, 2025. (Total: 49156 publications since 2009)
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Query Trace: Birkness K[original query]
Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 µg/ml in MGIT.
Whitfield MG , Warren RM , Streicher EM , Sampson SL , Sirgel FA , van Helden PD , Mercante A , Willby M , Hughes K , Birkness K , Morlock G , van Rie A , Posey JE .
J Clin Microbiol 2015 type

Sequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms which do not confer resistance at a susceptibility breakpoint of 100 mug/ml pyrazinamide in MGIT within a cohort of isolates from South Africa and the US Centre for Disease Control.
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