Last data update: Apr 29, 2024. (Total: 46658 publications since 2009)
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Query Trace: Banks MM [original query] |
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Characteristics and Timing of Initial Virus Shedding in Severe Acute Respiratory Syndrome Coronavirus 2, Utah, USA.
Lewis NM , Duca LM , Marcenac P , Dietrich EA , Gregory CJ , Fields VL , Banks MM , Rispens JR , Hall A , Harcourt JL , Tamin A , Willardson S , Kiphibane T , Christensen K , Dunn AC , Tate JE , Nabity S , Matanock AM , Kirking HL . Emerg Infect Dis 2021 27 (2) 352-359 Virus shedding in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur before onset of symptoms; less is known about symptom progression or infectiousness associated with initiation of viral shedding. We investigated household transmission in 5 households with daily specimen collection for 5 consecutive days starting a median of 4 days after symptom onset in index patients. Seven contacts across 2 households implementing no precautionary measures were infected. Of these 7, 2 tested positive for SARS-CoV-2 by reverse transcription PCR on day 3 of 5. Both had mild, nonspecific symptoms for 1-3 days preceding the first positive test. SARS-CoV-2 was cultured from the fourth-day specimen in 1 patient and from the fourth- and fifth-day specimens in the other. We also describe infection control measures taken in the households that had no transmission. Persons exposed to SARS-CoV-2 should self-isolate, including from household contacts, wear a mask, practice hand hygiene, and seek testing promptly. |
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