Advanced Molecular Detection Clips Content (Published on 09/23/2021)
NEWS
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Leader of WHO's new pandemic hub: improve data flow to extinguish outbreaks
Maxmen A. Nature, Sep 21, 2021. -
SARS-like viruses may jump from animals to people hundreds of thousands of times a year
Kupferschhmidt K. Science, Sep 15, 2021. -
Where Are the Tests?
Leonhardt D. New York Times, Sep 21, 2021. -
COVID vaccine immunity is waning--how much does that matter?
Dolgin E. Nature, Sep 17, 2021. -
Covid-19: Booster dose reduces infections and severe illness in over 60s, Israeli study reports
Mahase E. BMJ, Sep 17, 2021. -
FDA advisory panel recommends booster doses of Covid-19 vaccine only for older and high-risk Americans
Branswell H, Herper M. STAT, Sep 17, 2021. -
Could gene editing chickens prevent future pandemics?
Grover N. The Guardian, Sep 18, 2021.
CONCEPTS / COMMENTS
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Pandemics: Historically Slow "Learning Curve" Leading to Biomedical Informatics and Vaccine Breakthroughs.
Kulikowski Casimir A et al. Yearbook of medical informatics 2021 4 (1) 290-301
METHODS / TOOLS
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Trich-tracker - a practical tool to trace Trichinella spiralis transmission based on rapid, cost-effective sampling of genome-wide genetic variation.
Bilska-Zajac Ewa et al. International journal for parasitology 2021 9
EVOLUTION / ECOLOGY / POPULATIONS
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A genomic snapshot of Salmonella enterica serovar Typhi in Colombia.
Guevara Paula Diaz et al. PLoS neglected tropical diseases 2021 9 (9) e0009755 -
A 3,000-year-old, basal S. enterica lineage from Bronze Age Xinjiang suggests spread along the Proto-Silk Road.
Wu Xiyan et al. PLoS pathogens 2021 9 (9) e1009886 -
When specialized clones go global.
Wirth Thierry et al. Nature microbiology 2021 9 -
Dissemination of Mycobacterium abscessus via global transmission networks.
Ruis Christopher et al. Nature microbiology 2021 9 -
The origins of SARS-CoV-2: A critical review.
Holmes Edward C et al. Cell 2021 9 (19) 4848-4856 -
Coronaviruses with a SARS-CoV-2-like receptor-binding domain allowing ACE2-mediated entry into human cells isolated from bats of Indochinese peninsula
Temmam S, et al. Research Square, Sep 17, 2021. -
The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages.
Martin Darren P et al. Cell 2021 9 -
Exploiting genomic surveillance to map the spatio-temporal dispersal of SARS-CoV-2 spike mutations in Belgium across 2020.
Bollen Nena et al. Scientific reports 2021 9 (1) 18580 -
SARS-CoV-2 Quasispecies Provides an Advantage Mutation Pool for the Epidemic Variants.
Sun Fengming et al. Microbiology spectrum 2021 8 (1) e0026121 -
Spatiotemporal analyses illuminate the competitive advantage of a SARS-CoV-2 variant of concern over a variant of interest
Russell A, et al. medRxiv, Sep 20, 2021. -
The biological and clinical significance of emerging SARS-CoV-2 variants.
Tao Kaiming et al. Nature reviews. Genetics 2021 9
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Spread of SARS-CoV-2 Delta variant infections bearing the S:E484Q and S:T95I mutations in July and August 2021 in France
Verdurme L, et al. medRxiv, Sep 16, 2021. -
The spatial-temporal dynamics of respiratory syncytial virus infections across the east-west coasts of Australia during 2016-17.
Robertson Mark et al. Virus evolution 2021 9 (2) veab068 -
A systematic review on global RSV genetic data: Identification of knowledge gaps.
Langedijk Annefleur C et al. Reviews in medical virology 2021 9 e2284
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Emergence and adaptive evolution of influenza D virus.
He Wan-Ting et al. Microbial pathogenesis 2021 9 105193 -
Integrating animal movements with phylogeography to model the spread of PRRSV in the USA.
Makau Dennis N et al. Virus evolution 2021 9 (2) veab060
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Genomic epidemiology and antimicrobial resistance mechanisms of imported typhoid in Australia.
Ingle Danielle J et al. Antimicrobial agents and chemotherapy 2021 9 AAC0120021 -
Genomic Analysis of Carbapenem-Resistant Pseudomonas aeruginosa Isolated From Urban Rivers Confirms Spread of Clone Sequence Type 277 Carrying Broad Resistome and Virulome Beyond the Hospital.
Esposito Fernanda et al. Frontiers in microbiology 2021 9 701921 -
In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2.
Szemiel Agnieszka M et al. PLoS pathogens 2021 9 (9) e1009929 -
Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment.
Chen Liang et al. mSphere 2021 8 (4) e0048021 -
COVID-19 Cases from the First Local Outbreak of the SARS-CoV-2 B.1.1.7 Variant in China May Present More Serious Clinical Features: A Prospective, Comparative Cohort Study.
Song Yang et al. Microbiology spectrum 2021 8 (1) e0027321 -
High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape.
Schmidt Fabian et al. Nature 2021 9 -
Reinfection by the SARS-CoV-2 Gamma variant in blood donors in Manaus, Brazil
Prete CA, et al. medRxiv, Sep 16, 2021. -
Emergence of SARS-COV-2 Spike Protein Escape Mutation Q493R after Treatment for COVID-19
Focosi D, et al Emerg Infect Dis, Oct 2021. -
Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy.
Choudhary Manish C et al. medRxiv : the preprint server for health sciences 2021 9 -
Evidence of Artemisinin-Resistant Malaria in Africa
Balikagala B, et al. New Engl J Med, Sep 23, 2021. -
Multi-Year Mass-Trapping With Autocidal Gravid Ovitraps has Limited Influence on Insecticide Susceptibility in Aedes aegypti (Diptera: Culicidae) From Puerto Rico.
Hemme Ryan R et al. Journal of medical entomology 2021 9
DETECTION / DIAGNOSIS
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Trypanosome SL-RNA detection in blood and cerebrospinal fluid to demonstrate active gambiense human African trypanosomiasis infection.
Ngay Lukusa Ipos et al. PLoS neglected tropical diseases 2021 9 (9) e0009739 -
SARS-CoV-2 variant detection at a university dormitory using wastewater genomic tools.
Vo Van et al. The Science of the total environment 2021 9 149930
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SARS-CoV-2 variants in Paraguay: Detection and surveillance with a readily modifiable, multiplex real-time RT-PCR
Martinez M, et al. medRxiv, Sep 20, 2021. -
Subgenomic and negative sense RNAs are not markers of active replication of SARS-CoV-2 in nasopharyngeal swabs
Chamings A, et al. medRxiv, Sep 17, 2021. -
WHotLAMP: A simple, inexpensive, and sensitive molecular test for the detection of SARS-CoV-2 in saliva.
Ng David et al. PloS one 2021 9 (9) e0257464 -
Accessible Platform for High-Throughput COVID-19 Molecular Diagnostics and Genome Sequencing Using a Repurposed 3D Printer for RNA Extraction.
Vandelannoote Koen et al. ACS biomaterials science & engineering 2021 8 (9) 4669-4676 -
Molecular Mirror Technology Facilitates High-Throughput, Accurate SARS-CoV-2 Testing.
Realegeno Susan et al. Microbiology spectrum 2021 8 (1) e0039221 -
Longitudinal COVID-19 Surveillance and Characterization in the Workplace with Public Health and Diagnostic Endpoints.
Gunawardana Manjula et al. mSphere 2021 7 (4) e0054221 -
SARS-CoV-2 Delta Variant among Asiatic Lions, India.
Mishra Anamika et al. Emerging infectious diseases 2021 9 (10) 2723-2725 -
Genomic Sequencing of SARS-CoV-2 E484K Variant B.1.243.1, Arizona, USA.
Skidmore Peter T et al. Emerging infectious diseases 2021 9 (10) 2718-2720
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Genetic Diversity of SARS-CoV-2 among Travelers Arriving in Hong Kong.
Gu Haogao et al. Emerging infectious diseases 2021 9 (10) 2666-2668 -
Field evaluation of HIV-1 viral load monitoring in adults and children receiving antiretroviral treatment in Nigeria by dried blood spot testing with RealTime HIV-1 on m2000.
Tola Monday et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2021 1 104694
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Equine Herpesvirus 1 Variant and New Marker for Epidemiologic Surveillance, Europe, 2021.
Sutton Gabrielle et al. Emerging infectious diseases 2021 9 (10) 2738-2739 -
Host selection pattern and flavivirus screening of mosquitoes in a disturbed Colombian rainforest.
Hoyos Juliana et al. Scientific reports 2021 9 (1) 18656
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Survey of diagnostic and typing capacity for enterovirus infection in Italy and identification of two echovirus 30 outbreaks.
Fontana Stefano et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2021 3 104763
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Real-time PCR assay for detection and differentiation of Coccidioides immitis and Coccidioides posadasii from culture and clinical specimens.
Sudha Chaturvedi et al. PLoS Negl Trop Dis 2021 9 (9) e0009765 -
Emergomyces orientalis Emergomycosis Diagnosed by Metagenomic Next-Generation Sequencing.
He Da et al. Emerging infectious diseases 2021 9 (10) 2740-2742 -
A new duplex PCR assay for the rapid screening of mating-type idiomorphs of pathogenic Sporothrix species.
de Carvalho Jamile Ambrósio et al. Fungal biology 2021 9 (10) 834-843
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Prolonged outbreak of clonal, mupirocin-resistant methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit: association with personnel and a possible environmental reservoir, analyzed using whole genome sequencing.
Rubin Lorry G et al. American journal of infection control 2021 9 -
Escherichia coli O157:H7 Cluster Associated With Deer Harvested at a Single Wildlife Hunting Area, Oregon, 2017.
Stephen G Ladd-Wilson et al. Public Health Rep 2021 9 (5) 817-819 -
Tuberculosis in Australia's tropical north: a population-based genomic epidemiological study.
Meumann Ella M et al. The Lancet regional health. Western Pacific 2021 9 100229 -
Multiple Transmission Chains within COVID-19 Cluster, Connecticut, USA, 2020
Bart SM, et al. Emerg Infect Dis, Aug 23, 2021.
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Outbreak of SARS-CoV-2 B.1.617.2 (Delta) Variant Infections Among Incarcerated Persons in a Federal Prison--Texas, July-August 2021
Hagan LM, et al. MMWR, Sep 21, 2021.
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Air travel-related outbreak of multiple SARS-CoV-2 variants.
Dhanasekaran Vijaykrishna et al. Journal of travel medicine 2021 9 -
Phylodynamics reveals the role of human travel and contact tracing in controlling the first wave of COVID-19 in four island nations.
Douglas Jordan et al. Virus evolution 2021 9 (2) veab052 -
Genomic epidemiology of SARS-CoV-2 transmission lineages in Ecuador.
Gutierrez Bernardo et al. Virus evolution 2021 9 (2) veab051 -
Mumps virus outbreak related to a water pipe (narghile) shared smoking.
Aragón Andrés et al. Enfermedades infecciosas y microbiologia clinica (English ed.) 2021 9
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants.
Cevik Muge et al. Cell 2021 9
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Use of Pfizer-BioNTech COVID-19 Vaccine in Persons Aged ≥16 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, September 2021.
Dooling Kathleen et al. MMWR. Morbidity and mortality weekly report 2021 9 (38) 1344-1348
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Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions - United States, March-August 2021.
Self Wesley H et al. MMWR. Morbidity and mortality weekly report 2021 9 (38) 1337-1343
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Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel
Pilishvili T, et al. New Engl J Med, Sep 22, 2021.
HOST-MICROBE INTERACTIONS
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Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients.
Zhao Xiang-Na et al. Signal transduction and targeted therapy 2021 9 (1) 342
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice. Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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