Advanced Molecular Detection Clips Content (Published on 02/04/2021)
NEWS
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With All Eyes on Covid-19, Drug-Resistant Infections Crept In
Richtel M. New York Times, Jan 27, 2021. -
U.S. rushes to catch up in the race to detect mutant viruses
Stobbe M, Renault M. PBS, Feb 4, 2021. -
Why America is 'flying blind' to the coronavirus mutations racing across the globe
Wan W, Guarino B. Washington Post, Jan 29, 2021. -
SARS-CoV-2 Genome Sequencing Study Identifies 16 Viral Lineages in South Africa
GenomeWeb, Feb 2, 2020. -
UK Team Creates Five-Minute SARS-CoV-2 MDx With Rarely Used Isothermal Amplification Method
Johnson M. GenomeWeb, Feb 3, 2021. -
Dutch to roll out rapid breath tests for COVID-19
Reuters, Feb 3, 2021. -
With a seductive number, AstraZeneca study fueled hopes that eclipsed its data
Herper M, Branswell H. STAT, Feb 3, 2021. -
Oxford-AstraZeneca coronavirus vaccine may help prevent transmission, study finds
Adam K, Johnson CY. Washington Post, Feb 3, 2021. -
New variant COVID findings fuel more worries about vaccine resistance
Schnirring L. CIDRAP, Feb 2, 2021. -
Russia's COVID vaccine 92% effective, even in those over 60
Van Beusekom M. CIDRAP, Feb 2, 2021. -
Vaccinemakers ponder how to adapt to virus variants
Kupferschmidt K. Science, Jan 29, 2021. -
Johnson & Johnson's Vaccine Offers Strong Protection but Fuels Concern About Variants
Zimmer C, et al. New York Times, Jan 29, 2021. -
New clinical trials raise fears the coronavirus is learning how to resist vaccines
Baumgaertner E. Los Angeles Times, Jan 27, 2021.
EVENTS / TRAINING / WEB RESOURCES
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Investigation of novel SARS-CoV-2 variant: Variant of Concern 202012/01, Technical Briefing 5
(PDF) Public Health England, updated Feb 1, 2021.
CONCEPTS / COMMENTS
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Five reasons why researchers should learn to love the command line
Perkel JM. Nature, FEb 2, 2021. -
Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence.
Sabino Ester C et al. Lancet (London, England) 2021 Jan -
COVID-19 Impact on Diagnostic Innovations: Emerging Trends and Implications.
Oyewole Anne O et al. Diagnostics (Basel, Switzerland) 2021 Jan (2) -
SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants.
Moore John P et al. JAMA 2021 Jan -
Next-generation COVID-19 vaccines: here come the proteins.
Blakney Anna K et al. Lancet (London, England) 2021 Jan -
How to redesign COVID vaccines so they protect against variants
Callaway E, Ledford H. Nature, Jan 29, 2021. -
May I Borrow Your Covid Immunity?
Khamsi R. Wired, Jan 28, 2021. -
Antiviral drug discovery: preparing for the next pandemic.
Adamson Catherine S et al. Chemical Society reviews 2021 Feb
METHODS / TOOLS
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Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases.
Modlin Samuel J et al. Microbial genomics 2021 Jan -
Sequencing Data of North American SARS-CoV-2 Isolates Shows Widespread Complex Variants
Ford CT, et al. medRxiv, Jan 29, 2021. -
Estimation of the generation interval using pairwise relative transmission probabilities.
Leavitt Sarah V et al. Biostatistics (Oxford, England) 2021 Feb -
Factors influencing estimates of HIV-1 infection timing using BEAST.
Dearlove Bethany et al. PLoS computational biology 2021 Feb (2) e1008537
EVOLUTION / ECOLOGY / POPULATIONS
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Sixteen novel lineages of SARS-CoV-2 in South Africa
Tegally H, et al. Nat Med, Feb 2, 2021. -
Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
McCarthy KR, et al. Science, Feb 3, 2021. -
Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses OC43 and 229E.
Kistler Kathryn E et al. eLife 2021 Jan -
Epidemiological surveillance of chikungunya fever in Mexico since its introduction in 2014-2016 and identification of circulating genotypes.
Torres-Longoria Belem et al. Molecular biology reports 2021 Feb -
The genotype distribution and phylodynamic of measles viruses circulating in the east of China in postvaccine era, 2005-2017.
Lu Peishan et al. Journal of medical virology 2021 Feb
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Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease.
Wang Wei et al. PLoS pathogens 2021 Jan (1) e1009254 -
The microbiome of bat guano: for what is this knowledge important?
Dimkic Ivica et al. Applied microbiology and biotechnology 2021 Jan
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Transcontinental dissemination of the L2b/D-Da recombinant Chlamydia trachomatis Lymphogranuloma venereum (LGV) strain: need of broad multi-country molecular surveillance.
Borges Vítor et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Jan -
Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes.
Che You et al. Proceedings of the National Academy of Sciences of the United States of America 2021 Feb (6) -
The effect of SARS-CoV-2 variant B.1.1.7 on symptomatology, re-infection and transmissibility
Graham MS, et al. medRxiv, Jan 29, 2021. -
The basis of a more contagious 501Y.V1 variant of SARS-COV-2
Zhang G, et al. bioRxiv, Feb 2, 2021.
DETECTION / DIAGNOSIS
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Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial.
Scriba Thomas J et al. The Lancet. Infectious diseases 2021 Jan -
Transcriptomic signatures have a place in short-term prediction of incident tuberculosis.
Wejse Christian et al. The Lancet. Infectious diseases 2021 Jan -
Has the bubble burst for transcriptomics in tuberculosis diagnosis?
Walzl Gerhard et al. The Lancet. Infectious diseases 2021 Jan -
Transcriptomic signatures for diagnosing tuberculosis in clinical practice: a prospective, multicentre cohort study.
Hoang Long T et al. The Lancet. Infectious diseases 2021 Jan -
Detection of Bartonella quintana infection among the Homeless Population in Tokyo, Japan, from 2013-2015
Sasaki T, et al. Jpn J Infect Dis. 2021 Jan 29. doi: 10.7883/yoken.JJID.2020.505. -
Detection of SARS-CoV-2 and Its Mutated Variants via CRISPR-Cas13-Based Transcription Amplification.
Wang Yuxi et al. Analytical chemistry 2021 Jan -
Predictive power of SARS-CoV-2 wastewater surveillance for diverse populations across a large geographical range
Melvin RG, et al. medRxiv, Jan 30, 2021. -
Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019-United States, January 2020-February 2020.
Patel Monita R et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 02 (3) 403-410
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The Limit of Detection Matters: The Case for Benchmarking Severe Acute Respiratory Syndrome Coronavirus 2 Testing
Arnaout R, et al. Clin Infect Dis, Feb 3, 2021. -
Detection of SARS-CoV-2 from patient fecal samples by whole genome sequencing.
Papoutsis Andreas et al. Gut pathogens 2021 Jan (1) 7 -
RAY: CRISPR diagnostic for rapid and accurate detection of SARS-CoV2 variants on a paper strip
Kumar M, et al. medRxiv, Feb 3, 2021. -
Sensitivity of Dried Blood Spot Testing for Detection of Congenital Cytomegalovirus Infection.
Dollard Sheila C et al. JAMA pediatrics 2021 Feb e205441 -
NanoString Technology for Human Papillomavirus Typing.
Rajeevan Mangalathu S et al. Viruses 2021 Jan (2)
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Performance evaluation of fungal DNA PCR amplification from formalin-fixed paraffin-embedded tissue for diagnosis; experience of a tertiary reference laboratory.
Lysen Colleen et al. Mycoses 2021 Feb
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Molecular Epidemiology of Measles in California, USA - 2019.
Probert William S et al. The Journal of infectious diseases 2021 Feb -
Dynamic network connectivity influences the spread of a sub-lineage of porcine reproductive and respiratory syndrome virus.
Makau Dennis N et al. Transboundary and emerging diseases 2021 Feb -
Human T-cell lymphotropic virus type 1 transmission dynamics in rural villages in the democratic republic of the congo with high nonhuman primate exposure.
Halbrook Megan et al. PLoS neglected tropical diseases 2021 Jan (1) e0008923
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The first UK report of a rare Cryptosporidium hominis genetic variant isolated during a complex Scottish swimming pool outbreak.
Polubotho Padmaja et al. Journal of medical microbiology 2021 Jan
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines
Shen X, et al. bioRxiv, Jan 29, 2021. -
Spontaneous Emergence of Azithromycin Resistance in Independent Lineages of Salmonella Typhi in Northern India.
Carey Megan E et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Jan -
The effectiveness of the first dose of BNT162 b 2 vaccine in reducing SARS-CoV-2 infection 13-24 days after immunization: real-world evidence
Chodcik G, et al. medRxiv, Jan 29, 2021. -
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Voysey M, et al. Lancet, Jan 9, 2021. -
SARS-CoV-2 B.1.1.7 escape from mRNA vaccine-elicited neutralizing antibodies
Collier D, et al. medRxiv, Feb 2, 2021.
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Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia
Logunov DY, et al. Lancet, Feb 2, 2021.
HOST-MICROBE INTERACTIONS
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Post-Mendelian genetic model in COVID-19
Picchiotti N, et al. medRxiv, Jan 29, 2021. -
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response
Lin J, et al. Cell Host Microbe, Jan 29, 2021. -
Homotypic and Heterotypic Protection and Risk of Reinfection Following Natural Norovirus Infection in a Highly Endemic Setting.
Chhabra Preeti et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Jan (2) 222-229
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice. Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Genomics and Precision Public Health to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2023
- Page last updated:Sep 21, 2023
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