Advanced Molecular Detection Clips Content (Published on 01/07/2021)
NEWS
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COVID-19 Pandemic Accelerated Development of CRISPR as a Diagnostic Platform in 2020
Rizk C. GenomeWeb, Dec 28, 2020. -
COVID Assays Using CRISPR, Smartphones Show Potential for At-Home Testing
Rizk C. GenomeWeb, Dec 21, 2020. -
With limited surveillance of Covid-19 variant, it's deja vu all over again
Branswell H. STAT, Dec 31, 2020. -
Viral evolution may herald new pandemic phase
Kupferschmidt K. Science, Jan 7, 2021. -
Just How Much More Transmissible Is the New Coronavirus Variant?
Walker M. Medpage Today, Jan 2, 2021. -
You're Infected With the Coronavirus. But How Infected?
Mandavilli A. New York Times, Dec 29, 2020. -
Phase 3 trial of Novavax investigational COVID-19 vaccine opens
(news release) NIH, Dec 28, 2020.
EVENTS / TRAINING / WEB RESOURCES
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Important Changes to NCBI Accounts Coming in 2021
(announcement) NCBI, Jan 5, 2021.
CONCEPTS / COMMENTS
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Towards a coordinated strategy for intercepting human disease emergence in Africa
Forbes KM, et al. Lancet Microbe, Dec 17, 2020. -
SARS-CoV-2 spillover events
Zhou F, Shi ZL. Science, Jan 8, 2021. -
A guide to vaccinology: from basic principles to new developments
Pollard JA, Bijker EM. Nat Rev Immunol, Dec 22, 2020. -
Genomic Medicine and Advances in Vaccine Technology and Development in the Developing and Developed World.
Cianci Rossella et al. Vaccines 2020 Dec (1)
METHODS / TOOLS
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Improved metagenome binning and assembly using deep variational autoencoders.
Nissen Jakob Nybo et al. Nature biotechnology 2021 Jan -
A novel computational approach to reconstruct SARS-CoV-2 infection dynamics through the inference of unsampled sources of infection
Perera D, et al. medRxiv, Jan 6, 2021. -
Sequencing of Sars-CoV-2 genome using different Nanopore chemistries
Gonzalez-Recio O, et al. bioRxiv, Jan 2, 2021. -
Design of Specific Primer Set for Detection of B.1.1.7 SARS-CoV-2 Variant using Deep Learning
Lopez-Rincon A, et al. bioRxiv, Dec 29, 2020. -
Emerging SARS-CoV-2 diversity revealed by rapid whole genome sequence typing
Moustafa AM, Planet PJ. bioRxiv, Dec 28, 2020. -
Small-sample estimation of the mutational support and the distribution of mutations in the SARS-Cov-2 genome
Rana V, et al. medRxiv, Dec 28, 2020. -
Towards Unified Data Exchange Formats for Reporting Molecular Drug Susceptibility Testing.
Bonney Wilfred et al. Online journal of public health informatics 2020 (2) e14
EVOLUTION / ECOLOGY / POPULATIONS
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Genomic Epidemiology and Evolution of Escherichia coli in Wild Animals in Mexico.
Murphy Robert et al. mSphere 2021 Jan (1) -
Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a.
Joonlasak Khajohn et al. Virus research 2021 01 198233 -
Distinct mutations and lineages of SARS-CoV-2 virus in the early phase of COVID-19 global pandemic and subsequent global expansion
Chen Y, et al. bioRxiv, Jan 6, 2021. -
Emergence of a Highly Fit SARS-CoV-2 Variant
Baric RS. New Engl J Med, Dec 31, 2020. -
Paired SARS CoV-2 Spike Protein Mutations Observed During Ongoing SARS-CoV-2 Viral Transfer from Humans to Minks and Back to Humans
Burkholz S, et al. bioRxiv, Dec 29, 2020. -
Phylogenetic Analysis of the Dengue Virus Strains Causing the 2019 Dengue Fever Outbreak in Hainan, China.
Du Jiang et al. Virologica Sinica 2021 Jan
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Exploring utility of genomic epidemiology to trace origins of highly pathogenic influenza A/H7N9 in Guangdong.
Bai Ru et al. Virus evolution 2020 Jul (2) veaa097 -
Circulation of classic and recombinant human astroviruses detected in South Africa: 2009 to 2014.
Nadan Sandrama et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2020 Dec 104719 -
Simultaneous circulation of Zika, Dengue, and Chikungunya viruses and their vertical co-transmission among Aedes aegypti.
Teixeira Adriano Fernandes et al. Acta tropica 2021 Jan 105819 -
Vertebrate-Aedes aegypti and Culex quinquefasciatus (Diptera)-arbovirus transmission networks: Non-human feeding revealed by meta-barcoding and next-generation sequencing.
Estrada-Franco José Guillermo et al. PLoS neglected tropical diseases 2020 Dec (12) e0008867
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Distinguishing Pathovars from Nonpathovars: Escherichia coli.
Riley Lee W et al. Microbiology spectrum 2020 Dec (4) -
Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B.
Mansfield Michael J et al. PLoS pathogens 2020 Dec (12) e1009181 -
Whole-genome sequence analysis and comparisons between drug-resistance mutations and minimum inhibitory concentrations of Mycobacterium tuberculosis isolates causing M/XDR-TB.
Nonghanphithak Ditthawat et al. PloS one 2020 (12) e0244829 -
Genomic Variations in Drug Resistant Mycobacterium tuberculosis Strains Collected from Patients with Different Localization of Infection.
Chernyaeva Ekaterina et al. Antibiotics (Basel, Switzerland) 2020 Dec (1) -
SARS-CoV-2 RBD in vitro evolution follows contagious mutation spread, yet generates an able infection inhibitor
Zahradnik J, et al. bioRxiv, Jan 6, 2020. -
Global surveillance of potential antiviral drug resistance in SARS-CoV-2: proof of concept focussing on the RNA-dependent RNA polymerase
Mari A, et la. medRxiv, Jan 4, 2021. -
Characterization of SARS-CoV-2 ORF6 deletion variants detected in a nosocomial cluster during routine genomic surveillance, Lyon, France.
Quéromès Grégory et al. Emerging microbes & infections 2021 Jan 1-56
DETECTION / DIAGNOSIS
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Development of a sensitive molecular diagnostic assay for detecting Borrelia burgdorferi DNA from the blood of Lyme disease patients by digital PCR.
Das Srirupa et al. PloS one 2020 (11) e0235372 -
Implementing Building-Level SARS-CoV-2 Wastewater Surveillance on a University Campus
Gibas CJ, et al. medRxiv, Jan 4, 2021.
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Sub-5-minute Detection of SARS-CoV-2 RNA using a Reverse Transcriptase-Free Exponential Amplification Reaction, RTF-EXPAR
Carter JG, et al. medRxiv, Jan 4, 2021. -
Analysis and Forecasting of Global of RT-PCR Primers for SARS-CoV-2
Nayar G, et al. bioRxiv, Dec 28, 2020. -
Serodiagnostic antigens of Clonorchis sinensis identified and evaluated by high-throughput proteogenomics.
Cho Pyo Yun et al. PLoS neglected tropical diseases 2020 Dec (12) e0008998 -
Sensitive universal detection of blood parasites by selective pathogen-DNA enrichment and deep amplicon sequencing.
Flaherty Briana R et al. Microbiome 2021 Jan (1) 1
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Investigating hospital Mycobacterium chelonae infection using whole genome sequencing and hybrid assembly.
Gu Christopher H et al. PloS one 2020 (11) e0236533 -
Genomic Epidemiology of MRSA During Incarceration at a Large Inner-City Jail.
Popovich Kyle J et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Jan -
Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: insights from linking epidemiological and genetic data
Volz E, et al. medRxiv, Jan 4, 2021. -
Genomic Evidence of In-Flight Transmission of SARS-CoV-2 Despite Predeparture Testing.
Swadi Tara et al. Emerging infectious diseases 2021 Jan (3) -
HIV Care Prioritization using Phylogenetic Branch Length.
Moshiri Niema et al. Journal of acquired immune deficiency syndromes (1999) 2020 Dec -
Molecular epidemiology in the HIV and SARS-CoV-2 pandemics.
Lorenzo-Redondo Ramon et al. Current opinion in HIV and AIDS 2021 01 (1) 11-24
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Baden Lindsey R et al. The New England journal of medicine 2020 Dec -
Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2 leading to universal blueprints for vaccine designs.
Malone Brandon et al. Scientific reports 2020 Dec (1) 22375 -
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.
Polack Fernando P et al. The New England journal of medicine 2020 Dec -
Influenza vaccine effectiveness against hospitalization in the United States, 2019-2020.
Tenforde Mark W et al. The Journal of infectious diseases 2020 Dec
HOST-MICROBE INTERACTIONS
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Comprehensive analysis of the host-virus interactome of SARS-CoV-2
Chen Z, et al. bioRxiv, Jan 2, 2021. -
Meta-analysis of virus-induced host gene expression reveals unique signatures of immune dysregulation induced by SARS-CoV-2
Kuchi S, et al. bioRxiv, Dec 30, 2020. -
Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19.
Parkinson Nicholas et al. Scientific reports 2020 12 (1) 22303 -
The Intestinal and Oral Microbiomes Are Robust Predictors of Covid-19 Severity the Main Predictor of Covid-19-Related Fatality
Ward DV, et al medRxiv, Jan 6, 2021.
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice. Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Genomics and Precision Public Health to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Oct 1, 2023
- Page last updated:Nov 16, 2023
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