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Public Health Genomics and Precision Health Knowledge Base (v9.0)
PHGKB
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Public Health Genomics Branch
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All of Us Reports and Publications Database|Home|PHGKB
All of Us Reports and Publications Database
All of Us Publications Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: Apr 12, 2024
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An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction.
Jingning Zhang, et al. bioRxiv : the preprint server for biology 2023 0 0.
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Benchmarking multi-ancestry prostate cancer polygenic risk scores in a real-world cohort.
Yajas Shah, et al. PLoS computational biology 2024 0 0. (4) e1011990
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Genes associated with depression and coronary artery disease are enriched for cardiomyopathy and inflammatory phenotypes
Singh K, et al. Nature Mental Health 05 April 2024
Pleiotropic effects of the JAK2V617F mutation: a PHEWAS AND LABWAS study
Teymourzadeh A, et al, Journal of the American College of Cardiology, 83(13 Suppl) 2 April 2024, 1807
High-proportion spliced-in titin truncating variants and African aancestry: insights from the All of Us Research Program
Shetty NS, et al. J Am Coll Cardiol. 2024 Apr, 83 (13_Supplement) 527
Global genomic diversity for All of Us
Koch L. Nat Rev Genet (2024). https://doi.org/10.1038/s41576-024-00727-9
Abstract 2211: ALDH2 deficiency and alcohol intake: Opportunity for precision cancer prevention
Forman D, et al. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 2211.
‘All of Us’ genetics chart stirs unease over controversial depiction of race
Kozlov M. Nature NEWS, February 23, 2024
275 million new genetic variants identified in NIH precision medicine data
Press Team at NIH All of Us Research Program , February 19, 2024
P161: A genetics-first approach to identify novel variants of the calcium sensing receptor associated with autosomal dominant hypocalcemia type 1*
Chang J, et al. Genetics in Medicine Open, 2 (Suppl 1), 101058, 2024
O01: Using multiplexed functional data to reduce the VUS burden in populations underrepresented in genomic medicine
Dawood M, et al. Genetics in Medicine Open, 2 (Suppl 1), 101010, 2024
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry
Srushti LJ, et al. MEDRXIV March 13, 2024
O09: Phenome-wide studies of hereditary transthyretin amyloidosis in the All of Us research program
Williams-Rogers C et al. Genetics in Medicine Open, 2(Suppl 1), 101013, 2024
P876: Effects of social determinants of health on diagnosis of neurofibromatosis type 1 within the All of Us Research Program
Felker S & Barsh G, Genetics in Medicine Open, 2(Suppl 1), 101790, 2024
P262: Assessing urolithiasis polygenic risk score predictive performance across Black and White population groups: Insights from the All of Us database
Salem A, et al. Genetics in Medicine Open 2(Suppl 1); 2024, 101158
All of Us Program Illustrates What Less-Diverse Genomics Studies Might Be Missing.
Rita Rubin, et al. JAMA 2024 0 0.
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Ken Suzuki, et al. Nature 2024 0 0.
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Researchers optimize genetic tests for diverse populations to tackle health disparities
NIH, February 2024
PheWAS analysis on large-scale biobank data with PheTK
Tran TC, et al, MEDRXIV, February 13, 2024
The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities.
Eric Venner, et al. Commun Biol 2024 0 0. (1) 174
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Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.
Niall J Lennon, et al. Nat Med 2024 0 0. (2) 480-487
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Genomic data in the All of Us Research Program.
The All of Us Research Program Genomics Investigators, et al. Nature 2024 0 0.
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APOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous Malformation.
Daniela Renedo, et al. JAMA Netw Open 2024 0 0. (2) e2355368
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Ambitious survey of human diversity yields millions of undiscovered genetic variants Analysis of the ‘All of Us’ genomic data set begins to tackle inequities in genetics research.
M Koslov, Nature, February 19, 2024
Improving genetic risk modeling of dementia from real-world data in underrepresented populations
Chang T, et al. MEDRXIV, February 6, 2024
Multi-class Modeling Identifies Shared Genetic Risk for Late-onset Epilepsy and Alzheimer’s
Fu M, et al. MEDRXIV, February 5, 2024
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing.
Amy J Turner, et al. Clin Transl Sci 2023 0 0. (1) e13699
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High-proportion spliced-in titin truncating variants in African and European ancestry in the All of Us Research Program
Shetty NS, et al. Nature Cardiovascular Research, January 15, 2024
AB8 Polygenic Resistance to Blood Pressure Treatment and Stroke Risk
Huo S, et al. Stroke; 55 (suppl 1), February 2024
Mendelian Randomization Analysis Supports Causal Effect of Type II Diabetes Mellitus on Onychomycosis
Choo Z & Lipner S. Skin Appendage Disorders, Published online January 22, 2024
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 18, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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