About Advanced Molecular Detection Clips
Clips are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. Special emphasis is given to the use of next-generation genetic sequencing in infectious disease public health surveillance, investigation, and development of new diagnostics and interventions. The collection is not comprehensive but aims to capture highlights, while surveying a wide range of topics. CDC-authored articles are flagged. Items marked I&E address aspects of implementation or evaluation in clinical or public health practice.
Advanced Molecular Detection Clips Content
DNA Replication on Film
GenomeWeb, Jun 22, 2017.
Leprosy Relapse, Reinfection Detected in Proof-of-Principle Sequencing Study
GenomeWeb, Jun 16, 2017.
Modified viruses deliver death to antibiotic-resistant bacteria
Reardon S. Nature, Jun 21, 2017.
A Few Genetic Tweaks To Chinese Bird Flu Virus Could Fuel A Human Pandemic
Greenfield-Boyce N. NPR,
Polio outbreak is reported in Syria, WHO says
Branswell H. STAT, Jun 8, 2017.
First-in-human study will test novel malaria vaccine approach
Healio, Jun 11, 2017.
Brain-Invading Tapeworm That Eluded Doctors Spotted by New DNA Test
McGowan K. Sci Am, Jun 22, 2017.
Swipe right for science: Papr app is Tinder for preprints
McKenzie L. Nature, Jun 16, 2017.
EVENTS / TRAINING / WEB RESOURCES
Clear off the table (Old but still good advice on presenting data tables)
(blog post) Dark Horse Analytics, March 2014.
CONCEPTS / COMMENTS
Precision Medicine Requires Precision Laboratories.
Rajeevan Mangalathu S et al. The Journal of molecular diagnostics : JMD 2017 Mar (2) 226-229
Infectious diseases: Predictions of virus spillover across species.
Lloyd-Smith James O et al. Nature 2017 Jun
The Human Microbiome and the Missing Heritability Problem
Sandoval-Motta S, et al. Front Genet, Jun 13, 2017.
Cell-free synthetic biology for in vitro prototype engineering.
Moore Simon J et al. Biochemical Society transactions 2017 Jun (3) 785-791
METHODS / TOOLS
Applications of optical DNA mapping in microbiology.
Bogas Diana et al. BioTechniques 2017 Jun (6) 255-267
A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.
Emond-Rheault Jean-Guillaume et al. Frontiers in microbiology 2017 996
Flavivirus and Filovirus EvoPrinters: New alignment tools for the comparative analysis of viral evolution.
Brody Thomas et al. PLoS neglected tropical diseases 2017 Jun (6) e0005673
Full-genome amplification and sequencing of Zika viruses using a targeted amplification approach.
Leguia Mariana et al. Journal of virological methods 2017 Jun
Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids.
Cuypers Bart et al. Scientific reports 2017 Jun (1) 3725
From complex gut communities to minimal microbiomes via cultivation.
Clavel Thomas et al. Current opinion in microbiology 2017 Jun 148-155
EVOLUTION / ECOLOGY / POPULATIONS
Population Genomics of Legionella longbeachae and Hidden Complexities of Infection Source Attribution.
Bacigalupe Rodrigo et al. Emerging infectious diseases 2017 May (5) 750-757
Bacterial community dynamics in a cooling tower with emphasis on pathogenic bacteria and Legionella species using universal and genus-specific deep sequencing.
Pereira Rui P A et al. Water research 2017 Jun 363-376
Detection of yellow fever virus genomes from four imported cases in China.
Cui Shujuan et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2017 Jun
Genotype diversity and molecular evolution of noroviruses: A 30-year (1982-2011) comprehensive study with children from Northern Brazil.
Siqueira Jones Anderson Monteiro et al. PloS one 2017 (6) e0178909
Global patterns in coronavirus diversity.
Anthony Simon J et al. Virus evolution 2017 Jan (1) vex012
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens.
Jiang Xinglin et al. Nature communications 2017 Jun 15784
Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli.
Hazen Tracy H et al. Scientific reports 2017 Jun (1) 3513
Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia.
Mowlaboccus Shakeel et al. Emerging infectious diseases 2017 Aug (8)
Whole genome characterization of a naturally occurring vancomycin-dependent Enterococcus faecium from a patient with bacteremia.
Mitchell Stephanie L et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Aug 96-99
Three mutations switch H7N9 influenza to human-type receptor specificity.
de Vries Robert P et al. PLoS pathogens 2017 Jun (6) e1006390
Genetic indicators of drug resistance in the highly repetitive genome of Trichomonas vaginalis.
Bradic Martina et al. Genome biology and evolution 2017 Jun
DETECTION / DIAGNOSIS
Multiplex tests to identify gastrointestinal bacteria, viruses and parasites in people with suspected infectious gastroenteritis: a systematic review and economic analysis.
Freeman Karoline et al. Health technology assessment (Winchester, England) 2017 Apr (23) 1-188
Highly Multiplex Real-Time PCR-Based Screening for Blood-Borne Pathogens on an OpenArray Platform.
Grigorenko Elena et al. The Journal of molecular diagnostics : JMD 2017 Jun
Time to review the gold standard for genotyping vancomycin-resistant enterococci in epidemiology: Comparing whole-genome sequencing with PFGE and MLST in three suspected outbreaks in Sweden during 2013-2015.
Lytsy Birgitta et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Jun
Strain-level metagenomic analysis of the fermented dairy beverage nunu highlights potential food safety risks.
Walsh Aaron M et al. Applied and environmental microbiology 2017 Jun
Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases.
Stefani Mariane M A et al. PLoS neglected tropical diseases 2017 Jun (6) e0005598
Surveillance of upper respiratory infections by using newly multiplex PCR assay compared to conventional methods during influenza season in Taiwan.
Chiu Shu-Chun et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2017 Jun
Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs.
Kandathil Abraham J et al. Annals of internal medicine 2017 Jun
A multi-template multiplex PCR assay for hepatitis B virus and human β-globin.
Adeyemi Oluwapelumi O et al. Journal of medical virology 2017 Jun
An enhanced Enterovirus surveillance system allows identification and characterization of rare and emerging respiratory enteroviruses in Denmark, 2015-16.
Barnadas Céline et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2017 May 40-44
Point of care diagnosis of multiple schistosome parasites: Species-specific DNA detection in urine by loop-mediated isothermal amplification (LAMP).
Lodh Nilanjan et al. Acta tropica 2017 Jun 125-129
LAMPhimerus: A novel LAMP assay for detecting Amphimerus sp. DNA in human stool samples.
Cevallos William et al. PLoS neglected tropical diseases 2017 Jun (6) e0005672
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
Whole genome sequencing analyses of Listeria monocytogenes that persisted in a milkshake machine for a year and caused illnesses in Washington State.
Li Zhen et al. BMC microbiology 2017 Jun (1) 134
Multi-drug resistant Klebsiella pneumoniae strains circulating in hospital setting: whole-genome sequencing and Bayesian phylogenetic analysis for outbreak investigations.
Cella Eleonora et al. Scientific reports 2017 Jun (1) 3534
Whole-genome sequencing for identification of the source in hospital-acquired Legionnaires' disease.
Rosendahl Madsen A M et al. The Journal of hospital infection 2017 Apr
Outbreak of non-tuberculous mycobacteria skin or soft tissue infections associated with handling fish - New York City, 2013-2014.
Yacisin K et al. Epidemiology and infection 2017 Jun 1-11
Measles Outbreak with Unique Virus Genotyping, Ontario, Canada, 2015.
Thomas Shari et al. Emerging infectious diseases 2017 Jul (7) 1063-1069
ANTIMICROBIALS / VACCINES / INTERVENTIONS
An update on Zika vaccine developments.
Durbin Anna et al. Expert review of vaccines 2017 Jun
Host and viral traits predict zoonotic spillover from mammals.
Olival Kevin J et al. Nature 2017 Jun
Host gene expression analysis in Sri Lankan melioidosis patients.
Krishnananthasivam Shivankari et al. PLoS neglected tropical diseases 2017 Jun (6) e0005643
Cesarean or Vaginal Birth Does Not Impact the Longitudinal Development of the Gut Microbiome in a Cohort of Exclusively Preterm Infants.
Stewart Christopher J et al. Frontiers in microbiology 2017 1008
Environmental factors dominate over host genetics in shaping human gut microbiota composition
D Rothschild et al, bioRxiv, Jun 2017.
Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Apr 26, 2017
- Page last updated:Jun 22, 2017
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